Levy J A
Department of Medicine, University of California, San Francisco 94143-1270, USA.
Lancet. 1997 Feb 22;349(9051):558-63. doi: 10.1016/S0140-6736(97)80119-5.
Three new human herpesviruses have been recognised in the past decade, and add further to our knowledge of human diseases with potential viral aetiologies. These viruses can be included with the other known human herpesviruses found in normal body secretions, particularly saliva. HHV6 and HHV7 have been associated with febrile illnesses and the childhood disease, exanthem subitum. HHV8 seems to resemble Epstein-Barr virus in its possible transforming properties and poses challenging questions for researchers directed at determining its potential role in lymphomas and Kaposi's sarcoma. Research on these herpesviruses can provide valuable new insights into virus/host relationships and mechanisms involved in replicative and latent stages of virus infection.
在过去十年中，已识别出三种新的人类疱疹病毒，这进一步扩充了我们对可能由病毒引发病因的人类疾病的认识。这些病毒可与在正常身体分泌物（尤其是唾液）中发现的其他已知人类疱疹病毒归为一类。HHV6和HHV7与发热性疾病及儿童疾病幼儿急疹有关。HHV8在其可能的转化特性方面似乎与爱泼斯坦-巴尔病毒相似，这给致力于确定其在淋巴瘤和卡波西肉瘤中潜在作用的研究人员提出了具有挑战性的问题。对这些疱疹病毒的研究可为病毒/宿主关系以及病毒感染复制和潜伏阶段所涉及的机制提供宝贵的新见解。
