Mises J, Moussalli F, Delegue L, Dessertenne J, Beringer A, Poncet E, Navelet Y
Rev Electroencephalogr Neurophysiol Clin. 1977 Jan-Mar;7(1):128-31. doi: 10.1016/s0370-4475(77)80046-4.
The authors studied 11 children (mean age 5 1/2 years) before and during anaesthesia, and then several times from 1 to 6 hours after the injection of althesin. The anaesthetic agent was either pure althesin or althesin combined with dextromoramide. The electroclinical correlations described for adults are also found in children: slow waves, discontinuous and then isoelectric recording during the operation stage, then rapid recovery after ending drug administration. The special interest of this study was the analysis of E.E.G. recordings during the hours following clinical recovery: only once was the recording like that of full consciousness. Repeated recordings were all of drowsiness and even sleep, despite the clinical state of the subject. A short associated study concerns the E.E.G. of neonates during their first 24 hours, born to mothers anaesthetised with alfathesin.
作者在麻醉前和麻醉期间对11名儿童(平均年龄5.5岁)进行了研究,然后在注射阿法沙辛后1至6小时内多次进行研究。麻醉剂要么是纯阿法沙辛,要么是阿法沙辛与右吗拉胺联合使用。在成人中描述的电临床相关性在儿童中也能发现:手术阶段出现慢波、不连续然后等电位记录,然后在药物给药结束后迅速恢复。这项研究的特别之处在于对临床恢复后数小时内脑电图记录的分析:只有一次记录类似于完全清醒时的记录。尽管受试者的临床状态良好,但重复记录均显示为嗜睡甚至睡眠状态。一项简短的相关研究涉及用阿法沙辛麻醉的母亲所生新生儿出生后头24小时的脑电图情况。