Sancho E, Ferrando M D, Fernández C, Andreu E
Faculty of Biological Sciences, University of Valencia, Dr. Moliner 50, Valencia, Burjasot, 46100, Spain.
Ecotoxicol Environ Saf. 1998 Oct;41(2):168-75. doi: 10.1006/eesa.1998.1689.
This paper deals with the effect of fenitrothion (0.04 mg/liter) on the energy metabolism of the European eel, Anguilla anguilla, and its recovery from intoxication. Various parameters such as glycogen, lactate, proteins, total lipids, and glucose in eel liver and blood were analyzed after 2, 8, 12, 24, 32, 48, 56, 72, and 96 h of fenitrothion exposure. Subsequently, the fish were allowed recovery periods of 8, 12, 24, 48, 72, 96, 144, and 192 h in clean water, and the same parameters were evaluated. Liver glycogen and lipid contents decreased significantly during the exposure, while blood glucose levels increased markedly. Liver and blood lactate values increased during pesticide exposure, while proteins were decreased in comparison to unexposed controls. Most of the metabolic disorders did not persist after less than a week of recovery in clean water. The observed effects of fenitrothion on fish metabolism are discussed in relation to a stress syndrome, and probable reasons for alterations are also discussed.
本文探讨了杀螟硫磷（0.04毫克/升）对欧洲鳗鲡（Anguilla anguilla）能量代谢的影响及其从中毒状态的恢复情况。在杀螟硫磷暴露2、8、12、24、32、48、56、72和96小时后，分析了鳗鲡肝脏和血液中的各种参数，如糖原、乳酸、蛋白质、总脂质和葡萄糖。随后，让鱼在清洁水中恢复8、12、24、48、72、96、144和192小时，并评估相同的参数。暴露期间肝脏糖原和脂质含量显著下降，而血糖水平显著升高。农药暴露期间肝脏和血液中的乳酸值升高，而与未暴露的对照组相比蛋白质减少。在清洁水中恢复不到一周后，大多数代谢紊乱并未持续。结合应激综合征讨论了观察到的杀螟硫磷对鱼类代谢的影响，并讨论了变化的可能原因。
