• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Enzyme I: the first protein and potential regulator of the bacterial phosphoenolpyruvate: glycose phosphotransferase system.

作者信息

Chauvin F, Brand L, Roseman S

机构信息

Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.

出版信息

Res Microbiol. 1996 Jul-Sep;147(6-7):471-9. doi: 10.1016/0923-2508(96)84001-0.

DOI:10.1016/0923-2508(96)84001-0
PMID:9084757
Abstract
摘要

相似文献

1
Enzyme I: the first protein and potential regulator of the bacterial phosphoenolpyruvate: glycose phosphotransferase system.
Res Microbiol. 1996 Jul-Sep;147(6-7):471-9. doi: 10.1016/0923-2508(96)84001-0.
2
Identification of the N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system produced by proteolytic digestion.通过蛋白酶消化鉴定大肠杆菌磷酸烯醇丙酮酸:糖磷酸转移酶系统中酶I的N端结构域。
Arch Biochem Biophys. 1994 Jul;312(1):121-4. doi: 10.1006/abbi.1994.1289.
3
The N-terminal domain of Escherichia coli enzyme I of the phosphoenolpyruvate/glycose phosphotransferase system: molecular cloning and characterization.磷酸烯醇丙酮酸/葡萄糖磷酸转移酶系统中大肠杆菌酶I的N端结构域:分子克隆与特性分析
Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7028-31. doi: 10.1073/pnas.93.14.7028.
4
Influence of phosphoenolpyruvate and magnesium ions on the quaternary structure of enzyme I of the phosphotransferase system from gram-positive bacteria.磷酸烯醇丙酮酸和镁离子对革兰氏阳性菌磷酸转移酶系统中酶I四级结构的影响。
Biochemistry. 1995 Dec 5;34(48):15700-3. doi: 10.1021/bi00048a014.
5
The monomer/dimer transition of enzyme I of the Escherichia coli phosphotransferase system.大肠杆菌磷酸转移酶系统中酶I的单体/二聚体转变
J Biol Chem. 2006 Jun 30;281(26):17570-8. doi: 10.1074/jbc.M508965200. Epub 2006 Mar 19.
6
Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein.磷酸化酶I的结构,磷酸烯醇丙酮酸:糖磷酸转移酶系统的糖转运信号蛋白。
Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16218-23. doi: 10.1073/pnas.0607587103. Epub 2006 Oct 19.
7
Properties of the C-terminal domain of enzyme I of the Escherichia coli phosphotransferase system.大肠杆菌磷酸转移酶系统中酶I的C末端结构域的特性
J Biol Chem. 2006 Jun 30;281(26):17579-87. doi: 10.1074/jbc.M508966200. Epub 2006 Mar 19.
8
Importance of the region around glycine-338 for the activity of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.甘氨酸-338周围区域对大肠杆菌磷酸烯醇丙酮酸:糖磷酸转移酶系统中酶I活性的重要性。
Biochemistry. 1996 Jan 9;35(1):236-42. doi: 10.1021/bi952052k.
9
Transient state kinetics of Enzyme I of the phosphoenolpyruvate:glycose phosphotransferase system of Escherichia coli: equilibrium and second-order rate constants for the phosphotransfer reactions with phosphoenolpyruvate and HPr.大肠杆菌磷酸烯醇丙酮酸:葡萄糖磷酸转移酶系统中酶I的瞬态动力学:与磷酸烯醇丙酮酸和组氨酸磷酸载体蛋白(HPr)进行磷酸转移反应的平衡常数和二级速率常数
Biochemistry. 2005 Sep 27;44(38):12790-6. doi: 10.1021/bi0502846.
10
Enzyme I: the gateway to the bacterial phosphoenolpyruvate:sugar phosphotransferase system.酶I:细菌磷酸烯醇丙酮酸:糖磷酸转移酶系统的入口。
Arch Biochem Biophys. 2002 Jan 15;397(2):273-8. doi: 10.1006/abbi.2001.2603.

引用本文的文献

1
Elucidation of the Mechanisms of Inter-domain Coupling in the Monomeric State of Enzyme I by High-pressure NMR.高压 NMR 阐明酶 I 单体态中结构域间耦合的机制。
J Mol Biol. 2024 May 1;436(9):168553. doi: 10.1016/j.jmb.2024.168553. Epub 2024 Mar 27.
2
Solution Structure Ensembles of the Open and Closed Forms of the ∼130 kDa Enzyme I via AlphaFold Modeling, Coarse Grained Simulations, and NMR.通过 AlphaFold 建模、粗粒化模拟和 NMR 研究获得约 130 kDa 酶 I 的开环和闭环形式的溶液结构组合。
J Am Chem Soc. 2023 Jun 21;145(24):13347-13356. doi: 10.1021/jacs.3c03425. Epub 2023 Jun 6.
3
Protein Conformational Dynamics Underlie Selective Recognition of Thermophilic over Mesophilic Enzyme I by a Substrate Analogue.
蛋白质构象动力学是嗜热酶选择性识别底物类似物的基础。
Biomolecules. 2023 Jan 12;13(1):160. doi: 10.3390/biom13010160.
4
Synthetic Genetic Interactions Reveal a Dense and Cryptic Regulatory Network of Small Noncoding RNAs in Escherichia coli.合成遗传相互作用揭示了大肠杆菌中小非编码 RNA 的密集且隐匿的调控网络。
mBio. 2022 Aug 30;13(4):e0122522. doi: 10.1128/mbio.01225-22. Epub 2022 Aug 3.
5
A Single Point Mutation Controls the Rate of Interconversion Between the and Rotamers of the Histidine 189 χ2 Angle That Activates Bacterial Enzyme I for Catalysis.一个单点突变控制组氨酸189 χ2角的α和β旋转异构体之间的相互转换速率,该角激活细菌酶I以进行催化。
Front Mol Biosci. 2021 Jul 8;8:699203. doi: 10.3389/fmolb.2021.699203. eCollection 2021.
6
Structure elucidation of the elusive Enzyme I monomer reveals the molecular mechanisms linking oligomerization and enzymatic activity.阐明 elusive Enzyme I 单体的结构揭示了连接寡聚化和酶活性的分子机制。
Proc Natl Acad Sci U S A. 2021 May 18;118(20). doi: 10.1073/pnas.2100298118.
7
An allosteric pocket for inhibition of bacterial Enzyme I identified by NMR-based fragment screening.通过基于核磁共振的片段筛选鉴定出的用于抑制细菌酶I的变构口袋。
J Struct Biol X. 2020 Jul 21;4:100034. doi: 10.1016/j.yjsbx.2020.100034. eCollection 2020.
8
Hybrid Thermophilic/Mesophilic Enzymes Reveal a Role for Conformational Disorder in Regulation of Bacterial Enzyme I.杂合嗜热/嗜中温酶揭示构象无序在细菌酶 I 调控中的作用。
J Mol Biol. 2020 Jul 24;432(16):4481-4498. doi: 10.1016/j.jmb.2020.05.024. Epub 2020 Jun 3.
9
Potential Regulatory Role of Competitive Encounter Complexes in Paralogous Phosphotransferase Systems.竞争遭遇复合物在旁系磷酸转移酶系统中的潜在调控作用。
J Mol Biol. 2019 May 31;431(12):2331-2342. doi: 10.1016/j.jmb.2019.04.040. Epub 2019 May 6.
10
Reframing gene essentiality in terms of adaptive flexibility.从适应性灵活性的角度重新构建基因必需性。
BMC Syst Biol. 2018 Dec 17;12(1):143. doi: 10.1186/s12918-018-0653-z.