Wolinsky F D, Fitzgerald J F, Stump T E
Indiana University School of Medicine, Indianapolis, USA.
Am J Public Health. 1997 Mar;87(3):398-403. doi: 10.2105/ajph.87.3.398.
The purpose of this study was to prospectively assess the independent effect of hip fracture on mortalìty, hospitalization, and functional status.
Among 7527 members of the Longitudinal Study of Aging who were over age 70 at baseline, 368 persons with hip fracture occurring between 1984 and 1991 were identified. Median length of follow-up was 831 days.
Hip fracture was significantly related to mortality (adjusted hazards ratio [AHR] = 1.83; 95% confidence interval [CI] = 1.55, 2.16) when treated as a time-dependent covariate. This effect was concentrated in the first 6 months postfracture (AHR = 38.93, 95% CI = 29.58, 51.23, vs AHR = 1.17; 95% CI = 0.95, 1.44). Hip fracture significantly increased the likelihood of subsequent hospitalization (adjusted odds ratio = 3.31, 95% CI = 2.64, 4.15) and increased the number of subsequent episodes by 9.4%, the number of hospital days by 21.3%, and total charges by 16.3%. Hip fracture also increased the number of functional status dependencies.
The health of older adults deteriorates after hip fracture, and efforts to reduce the incidence of hip fracture could lower subsequent mortality, morbidity, and health services use.
本研究的目的是前瞻性评估髋部骨折对死亡率、住院情况和功能状态的独立影响。
在纵向衰老研究的7527名基线年龄超过70岁的成员中,确定了1984年至1991年间发生髋部骨折的368人。中位随访时间为831天。
当将髋部骨折作为时间依赖性协变量处理时,其与死亡率显著相关(调整后风险比[AHR]=1.83;95%置信区间[CI]=1.55,2.16)。这种影响集中在骨折后的前6个月(AHR=38.93,95%CI=29.58,51.23,对比AHR=1.17;95%CI=0.95,1.44)。髋部骨折显著增加了随后住院的可能性(调整后优势比=3.31,95%CI=2.64,4.15),并使随后的发作次数增加了9.4%,住院天数增加了21.3%,总费用增加了16.3%。髋部骨折还增加了功能状态依赖的数量。
髋部骨折后老年人的健康状况恶化,降低髋部骨折发生率的努力可以降低随后的死亡率、发病率和医疗服务使用。