Lips P, Cooper C, Agnusdei D, Caulin F, Egger P, Johnell O, Kanis J A, Liberman U, Minne H, Reeve J, Reginster J Y, de Vernejoul M C, Wiklund I
Department of Endocrinology, Academisch Ziekenhuis Vrije Universiteit, Amsterdam, The Netherlands.
Osteoporos Int. 1997;7(1):36-8. doi: 10.1007/BF01623457.
The morbidity of osteoporosis is caused by fractures. Vertebral fractures lead to pain and disability and a decrease in quality of life. A Working Party of the European Foundation for Osteoporosis has developed a specific questionnaire for patients with established vertebral osteoporosis. This questionnaire is intended for use in clinical trials. The questionnaire consists of questions and visual analogue scales in the following domains: pain, activities of daily living, jobs around the house, mobility, leisure and social activities, general health perception and mood. The questionnaire has been translated from English into French, German, Italian, Hebrew, Swedish and Dutch. The questionnaire is currently being validated in a multicentre study involving patients with stable osteoporosis and control subjects. Preliminary results indicate that the reproducibility is sufficient and that the questionnaire is able to discriminate between patients with vertebral osteoporosis and control subjects.
骨质疏松症的发病率是由骨折引起的。椎体骨折会导致疼痛、残疾以及生活质量下降。欧洲骨质疏松症基金会的一个工作小组为已确诊的椎体骨质疏松症患者制定了一份特定问卷。该问卷旨在用于临床试验。问卷由以下领域的问题和视觉模拟量表组成：疼痛、日常生活活动、家务、行动能力、休闲和社交活动、总体健康认知和情绪。该问卷已从英语翻译成法语、德语、意大利语、希伯来语、瑞典语和荷兰语。目前正在一项涉及稳定型骨质疏松症患者和对照受试者的多中心研究中对该问卷进行验证。初步结果表明其再现性足够，且该问卷能够区分椎体骨质疏松症患者和对照受试者。
