非典型军团菌样生物：对人类致病的苛求性水相关细菌。

Atypical Legionella-like organisms: fastidious water-associated bacteria pathogenic for man.

作者信息

Cordes L G, Wilkinson H W, Gorman G W, Fikes B J, Fraser D W

出版信息

Lancet. 1979 Nov 3;2(8149):927-30. doi: 10.1016/s0140-6736(79)92623-0.

Abstract

A group of related bacteria designated atypical Legionella-like organisms (ALLO) has been identified. ALLO, like L. pneumophila, are fastidious gram-negative rods that grow well on charcoal yeast extract (CYE) agar and produce ground glass colonies and browning of modified yeast extract agar. Unlike L. pneumophila, ALLO do not grow well on Feeley-Gorman (FG) agar, and on CYE agar they fluoresce under longwave ultraviolet light. ALLO and L. pneumophila have a similar predominance of branched-chain forms among total cellular fatty acids but have distinctive fatty-acid profiles. 2 patients with culture-verified ALLO pneumonia and 10 with pneumonia of uncertain aetiology who seroconverted to ALLO offer evidence that ALLO may be a cause of community-acquired pneumonia. Like L. pneumophila, ALLO appear to be water-associated; both persons with culture-verified ALLO infection were exposed to fresh water or its contents before becoming ill, and two strains of ALLO were isolated from water or wet environments.

摘要

已鉴定出一组相关细菌，称为非典型嗜肺军团菌样生物（ALLO）。与嗜肺军团菌一样，ALLO是苛求性革兰氏阴性杆菌，在活性炭酵母提取物（CYE）琼脂上生长良好，产生毛玻璃样菌落，并使改良酵母提取物琼脂呈褐色。与嗜肺军团菌不同，ALLO在费利-戈尔曼（FG）琼脂上生长不佳，而在CYE琼脂上，它们在长波紫外线下会发出荧光。ALLO和嗜肺军团菌在总细胞脂肪酸中支链形式的占比相似，但具有独特脂肪酸谱。2例经培养证实为ALLO肺炎的患者和10例病因不明且血清转化为ALLO的肺炎患者提供了证据，表明ALLO可能是社区获得性肺炎的病因。与嗜肺军团菌一样，ALLO似乎与水有关；2例经培养证实为ALLO感染的患者在患病前均接触过淡水或其所含物质，并且从水或潮湿环境中分离出了两株ALLO。