Guthridge S L, Miller N C
Territory Health Services, Darwin.
Aust N Z J Public Health. 1996 Dec;20(6):657-60. doi: 10.1111/j.1467-842x.1996.tb01084.x.
We monitored the temperatures of batches of vaccine during transport and storage from a national warehouse to five Northern Territory vaccination clinics. Electronic temperature monitors were placed with vaccines, and were programmed to record the temperature every 30 minutes for up to three months. A diary was attached to each vaccine batch to record each change in location. The temperature recordings covered 8369 hours. There were regular temperature deviations outside the recommended range. In the hot climate of the Northern Territory, freezing is the greatest threat to vaccine potency. Recommendations from the study include: routine use of cold chain indicators, increased vaccine turnover and storage of vaccines within an operational temperature range of 4 to 8 degrees C. Research is needed to investigate the efficacy of heat-stable vaccines when stored at ambient temperatures and in air-conditioned environments.
我们监测了从国家仓库运往北领地五个疫苗接种诊所的多批疫苗在运输和储存过程中的温度。电子温度监测器与疫苗放置在一起，并设置为每30分钟记录一次温度，记录时长可达三个月。每批疫苗都附有一本日志，以记录每次位置变化。温度记录时长为8369小时。经常出现超出推荐范围的温度偏差。在北领地炎热的气候条件下，冻结对疫苗效力构成最大威胁。该研究提出的建议包括：常规使用冷链指标、提高疫苗周转率以及在4至8摄氏度的操作温度范围内储存疫苗。需要开展研究，以调查热稳定疫苗在常温及空调环境下储存时的效力。
