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血细胞比容作为穿透性创伤后严重损伤的预测指标。

Hematocrit as a predictor of significant injury after penetrating trauma.

作者信息

Paradis N A, Balter S, Davison C M, Simon G, Rose M

机构信息

Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

出版信息

Am J Emerg Med. 1997 May;15(3):224-8. doi: 10.1016/s0735-6757(97)90001-2.

Abstract

A study was undertaken to determine if there are differences in hematocrit (HCT) during the initial evaluation of patients with and without significant visceral intrathoracic or intraabdominal injury after penetrating trauma and, if so, the predictive value of this parameter. Sixty consecutive adults with potentially significant penetrating trauma who presented to an urban municipal trauma center during a 10-week period were studied. Diagnostic variables were recorded for all patients at risk for significant injury, defined as intrathoracic or intraabdominal injury requiring surgical intervention. Patients were ultimately grouped on the basis of operative findings or observation to discharge. Acquired variables included vital signs, initial HCT (HCT-0), HCT at 15 minutes (HCT-15), HCT at 30 minutes (HCT-30), and fluid administered. Twenty-one patients had significant injuries (INJ), and 39 did not (NO-INJ). INJ patients had lower HCT values than NO-INJ on presentation (35% +/- 6% and 41% +/- 5%, respectively). At presentation, a low HCT was predictive of significant injury, but a normal HCT did not preclude injury. The changes in HCT from arrival to 15 minutes, between INJ and NO-INJ patients, were similar (-1.5% +/- 3% and -0.6% +/- 3% respectively). Only when the decrease in HCT was > or =6.5% from presentation measurements was it predictive of injury. During the first 15 minutes a decrease in HCT of > or =6.5% had a positive predictive value and specificity of 1.0. The change in HCT between 15 and 30 minutes was less useful. There was a large difference between the amounts of fluid given to injured and uninjured patients, which may have been responsible for some of the differences in HCT between the two groups. These results show that HCT may have some diagnostic utility during the early management of penetrating trauma. Presentation with an HCT below normal, or an early decrease in HCT, is an indicator of potential injury. Although many patients with serious internal injuries do not manifest large decreases early after presentation, those who do have a high probability of internal injury. The lower the HCT, or the greater the decrease, the greater the probability that a significant injury exists.

摘要

本研究旨在确定穿透性创伤后有或无严重胸内或腹内脏器损伤的患者在初始评估时血细胞比容(HCT)是否存在差异,若存在差异,该参数的预测价值如何。对连续10周内到城市市级创伤中心就诊的60例有潜在严重穿透性创伤的成年人进行了研究。记录所有有严重损伤风险患者的诊断变量,严重损伤定义为需要手术干预的胸内或腹内损伤。患者最终根据手术结果或观察至出院情况进行分组。获取的变量包括生命体征、初始HCT(HCT-0)、15分钟时的HCT(HCT-15)、30分钟时的HCT(HCT-30)以及给予的液体量。21例患者有严重损伤(INJ组),39例无严重损伤(NO-INJ组)。INJ组患者就诊时的HCT值低于NO-INJ组(分别为35%±6%和41%±5%)。就诊时,低HCT可预测严重损伤,但正常HCT不能排除损伤。INJ组和NO-INJ组患者从就诊到15分钟时HCT的变化相似(分别为-1.5%±3%和-0.6%±3%)。仅当HCT较就诊时测量值下降≥6.5%时才提示有损伤。在最初15分钟内,HCT下降≥6.5%的阳性预测值和特异性为1.0。15至30分钟时HCT的变化作用较小。受伤患者和未受伤患者给予的液体量有很大差异,这可能是两组HCT差异的部分原因。这些结果表明,HCT在穿透性创伤的早期处理中可能具有一定的诊断价值。就诊时HCT低于正常或早期HCT下降是潜在损伤的一个指标。虽然许多有严重内伤的患者在就诊后早期不会出现大幅下降,但出现这种情况的患者内伤的可能性很高。HCT越低或下降幅度越大,存在严重损伤的可能性就越大。

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