一例致命的产后索氏梭菌相关性中毒性休克综合征。
A fatal postpartum Clostridium sordellii associated toxic shock syndrome.
作者信息
Bitti A, Mastrantonio P, Spigaglia P, Urru G, Spano A I, Moretti G, Cherchi G B
机构信息
Clinical Pathology Laboratory, A. Segni Hospital, Ozieri, Sassari, Italy.
出版信息
J Clin Pathol. 1997 Mar;50(3):259-60. doi: 10.1136/jcp.50.3.259.
Abstract
Clostridium sordellii is an infrequent human pathogen. It has been demonstrated to be occasionally responsible for myonecrosis or gas gangrene. Interestingly, in the obstetric literature, some cases of postpartum maternal deaths have been associated with C sordellii infection causing a rapidly lethal toxin mediated syndrome. This is the first reported case of postpartum death in a 29 year old woman, in which a toxigenic C sordellii was isolated from the patient's blood antemortem during the fatal toxic shock, strongly indicating its role in this rare syndrome.
摘要
索氏梭菌是一种不常见的人类病原体。已证明它偶尔会导致肌坏死或气性坏疽。有趣的是，在产科文献中，一些产后孕产妇死亡病例与索氏梭菌感染有关，可导致一种迅速致命的毒素介导综合征。这是首例报道的29岁女性产后死亡病例，在致命性中毒性休克期间从患者生前血液中分离出产毒素索氏梭菌，有力地表明了其在这种罕见综合征中的作用。
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本文引用的文献
1
Neonatal Clostridium sordellii toxic omphalitis.新生儿索氏梭菌中毒性脐炎
Pediatr Infect Dis J. 1993 Mar;12(3):253-7. doi: 10.1097/00006454-199303000-00020.
2
Rapid assay for detection of toxic shock syndrome toxin 1 from human sera.用于检测人血清中毒性休克综合征毒素1的快速检测法。
J Clin Microbiol. 1994 Feb;32(2):539-42. doi: 10.1128/jcm.32.2.539-542.1994.
3
Difference in susceptibility of various cell cultures to cytotoxic culture filtrates of Clostridium sordellii.
Microbiol Immunol. 1984;28(4):493-7. doi: 10.1111/j.1348-0421.1984.tb00700.x.
4
The toxins responsible for the lesions of Clostridium sordelli gas gangrene.
J Med Microbiol. 1969 Feb;2(1):37-53. doi: 10.1099/00222615-2-1-37.
5
Antibacterial susceptibility of Clostridium sordellii strains.索氏梭菌菌株的抗菌药敏性。
Zentralbl Bakteriol Mikrobiol Hyg A. 1986 May;261(3):345-9. doi: 10.1016/s0176-6724(86)80052-9.
6
Immunization of adult hamsters against Clostridium difficile-associated ileocecitis and transfer of protection to infant hamsters.成年仓鼠针对艰难梭菌相关性回盲肠炎的免疫接种及保护作用向幼龄仓鼠的转移。
Infect Immun. 1987 Dec;55(12):2984-92. doi: 10.1128/iai.55.12.2984-2992.1987.
7
Fatal acute spontaneous endometritis resulting from Clostridium sordelli.
Am J Clin Pathol. 1989 Jan;91(1):104-6. doi: 10.1093/ajcp/91.1.104.
8
Maternal deaths associated with Clostridium sordellii infection.
Am J Obstet Gynecol. 1989 Oct;161(4):987-95. doi: 10.1016/0002-9378(89)90768-0.
9
Clostridium sordellii bacteremia: case report and review.
Clin Infect Dis. 1992 Dec;15(6):950-4. doi: 10.1093/clind/15.6.950.
10
Comparison of Clostridium sordellii toxins HT and LT with toxins A and B of C. difficile.索氏梭菌毒素HT和LT与艰难梭菌毒素A和B的比较。
J Med Microbiol. 1992 Jan;36(1):30-6. doi: 10.1099/00222615-36-1-30.
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