Mardelli P G, Piebenga L W, Whitacre M M, Siegmund K D
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, USA.
Ophthalmology. 1997 Jun;104(6):945-8; discussion 949. doi: 10.1016/s0161-6420(97)30202-4.
The authors determined whether photorefractive keratectomy (PRK) affects Goldmann applanation readings in human eyes.
The intraocular pressure (IOP) of 111 patients was measured using Goldmann applanation tonometry at baseline and 12 months after PRK. Ultrasonic corneal thickness measurements and keratometry were also obtained. Contralateral eyes were used as controls.
There was a statistically significant decrease in mean tonometer readings in the treated eyes when compared with the control eyes (0.5 +/- 2.1 mmHg, P = 0.01) accompanied by a significant reduction in mean central pachymetry in the treated eyes (23 +/- 23 microns, P < 0.001). In the treated eyes, the mean spherical equivalent and mean central keratometry readings were significantly reduced by 3.3 +/- 1.5 and 2.2 +/- 1.2 diopters, respectively (P < 0.001).
Photorefractive keratectomy causes a mild lowering of the Goldmann tonometer readings. The reduction in IOP measurement is probably not enough to alter a therapeutic decision in an individual patient known to have glaucoma, but it may delay recognition and treatment of glaucoma.
作者确定了准分子激光角膜切削术（PRK）是否会影响人眼的Goldmann压平眼压测量值。
使用Goldmann压平眼压计在基线时和PRK术后12个月测量了111例患者的眼压。还进行了超声角膜厚度测量和角膜曲率测量。对侧眼用作对照。
与对照眼相比，治疗眼的眼压计平均读数有统计学意义的降低（0.5±2.1 mmHg，P = 0.01），同时治疗眼的平均中央角膜厚度显著降低（23±23微米，P < 0.001）。在治疗眼中，平均等效球镜度和平均中央角膜曲率读数分别显著降低了3.3±1.5和2.2±1.2屈光度（P < 0.001）。
准分子激光角膜切削术会导致Goldmann眼压计读数轻度降低。眼压测量值的降低可能不足以改变已知患有青光眼的个体患者的治疗决策，但可能会延迟青光眼的识别和治疗。
