Tabriz University of Medical Sciences, Nikookari Eye Hospital, Tabriz, Iran.
Graefes Arch Clin Exp Ophthalmol. 2013 Feb;251(2):603-8. doi: 10.1007/s00417-012-2142-1. Epub 2012 Sep 2.
The intraocular pressure (IOP) could be measured by both Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT). Although these two methods have been discussed widely after laser-assisted sub-epithelial keratectomy (LASIK), there is little data in the cases undergoing photorefractive keratectomy (PRK). We aimed to compare the changes of IOP measurements obtained by GAT and DCT after PRK for myopia/myopic astigmatism.
This prospective study enrolled 77 candidates (154 eyes) for PRK to correct myopia or myopic astigmatism and 30 matched patients (30 eyes) with myopia or myopic astigmatism who served as controls. Changes of the IOP measurements (ΔIOP) obtained by GAT and DCT before and at 6 months after PRK in the operated eyes, and at baseline and 6 months later in the controls, were documented. Changes of the central corneal thickness (ΔCCT) were determined in the same fashion.
The mean IOP readings obtained by DCT were comparable before and at 6 months after procedure (18.34 ± 3.03 mmHg and 17.87 ± 2.61 mmHg respectively, p = 0.41); whereas the mean IOP reading obtained by GAT decreased significantly 6 months postoperatively (17.92 ± 3.63 mmHg and 16.25 ± 2.66 mmHg, p < 0.001). A significant correlation was present between the ΔIOP obtained by GAT and ΔCCT (r = 0.61, p < 0.001). Similar correlation was not significant between the DCT-obtained ΔIOP and the ΔCCT (r = 0.07, p = 0.44). The mean ΔIOP obtained by GAT was significantly higher in the operated eyes than in the controls (-1.54 ± 1.45 vs 0.07 ± 0.44 mmHg, p = 0.02). The mean DCT-obtained ΔIOP was just marginally insignificant between the operated and nonoperated eyes (-0.63 ± 0.59 vs 0.02 ± 0.38 mmHg respectively; p = 0.09).
The authors recommend DCT after PRK in the cases with myopia or myopic astigmatism.
眼压（IOP）可通过 Goldmann 压平眼压测量（GAT）和动态轮廓眼压测量（DCT）进行测量。尽管这两种方法在激光辅助上皮下角膜切除术（LASIK）后已广泛讨论，但在光折射性角膜切除术（PRK）的情况下数据较少。我们旨在比较 GAT 和 DCT 在近视/近视散光 PRK 后测量的 IOP 变化。
这项前瞻性研究纳入了 77 名（154 只眼）接受 PRK 治疗近视或近视散光的候选者和 30 名匹配的近视或近视散光患者（30 只眼）作为对照组。记录术前和术后 6 个月接受 PRK 治疗的手术眼以及对照组的 GAT 和 DCT 测量的 IOP 变化（ΔIOP），并以相同方式确定中央角膜厚度（ΔCCT）的变化。
DCT 测量的平均 IOP 读数在术前和术后 6 个月时相当（分别为 18.34 ± 3.03 mmHg 和 17.87 ± 2.61 mmHg，p = 0.41）；而 GAT 测量的平均 IOP 读数在术后 6 个月时显著下降（17.92 ± 3.63 mmHg 和 16.25 ± 2.66 mmHg，p < 0.001）。GAT 获得的 ΔIOP 与 ΔCCT 之间存在显著相关性（r = 0.61，p < 0.001）。DCT 获得的 ΔIOP 与 ΔCCT 之间的相关性不显著（r = 0.07，p = 0.44）。GAT 获得的平均 ΔIOP 在手术眼中显著高于对照组（-1.54 ± 1.45 vs 0.07 ± 0.44 mmHg，p = 0.02）。DCT 获得的平均 ΔIOP 在手术眼和非手术眼之间仅略无统计学意义（分别为-0.63 ± 0.59 vs 0.02 ± 0.38 mmHg，p = 0.09）。
作者建议在近视或近视散光患者中 PRK 后使用 DCT。
