Manickam M, Ramanathan M, Jahromi M A, Chansouria J P, Ray A B
Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, India.
J Nat Prod. 1997 Jun;60(6):609-10. doi: 10.1021/np9607013.
Glucose levels in rats with hyperglycemia induced by streptozotocin were determined after i.p. administration of marsupsin (1), pterosupin (2), and pterostilbene (3), three important phenolic constituents of the heartwood of Pterocarpus marsupium. Marsupsin and pterostilbene significantly lowered the blood glucose level of hyperglycemic rats, and the effect was comparable to that of 1,1-dimethylbiguanide (metformin).
腹腔注射紫檀芪（1）、紫檀素（2）和白藜芦醇（3）（紫檀木心材的三种重要酚类成分）后，测定了链脲佐菌素诱导的高血糖大鼠的血糖水平。紫檀芪和白藜芦醇显著降低了高血糖大鼠的血糖水平，其效果与1,1 - 二甲基双胍（二甲双胍）相当。
