Bringmann G, Saeb W, Assi L A, François G, Sankara Narayanan A S, Peters K, Peters E M
Institut für Organische Chemie der Universität, Würzburg, Germany.
Planta Med. 1997 Jun;63(3):255-7. doi: 10.1055/s-2006-957666.
The known lupane-type triterpene betulinic acid (3) was isolated for the first time from Triphyophyllum peltatum and Ancistrocladus heyneanus. It was found to exhibit moderate to good in vitro antimalarial activity against asexual erythrocytic stages of the human malaria parasite Plasmodium falciparum. A first X-ray structure analysis succeeded after conversion into its benzyl ester 4.
已知的羽扇豆烷型三萜桦木酸（3）首次从盾叶三叉叶木和希氏钩枝藤中分离得到。发现它对人类疟原虫恶性疟原虫的无性红细胞阶段表现出中度至良好的体外抗疟活性。在将其转化为苄酯4后首次成功进行了X射线结构分析。
