免疫学中的脂质体：针对含抗原脂质体的免疫反应。
Liposomes in immunology: the immune response against antigen-containing liposomes.
作者信息
van Rooijen N, van Nieuwmegen R
出版信息
Immunol Commun. 1977;6(5):489-98. doi: 10.3109/08820137709094148.
PMID:924513
Abstract
Three ways of antigen administration to rabbits were compared with respect to the resulting immune responses. Antigen was administered free in solution, entrapped in liposomes or free in solution but together with empty liposomes. Liposomal material showed adjuvant activity when injected together with free antigen, but a much stronger adjuvant effect was found when antigen was injected entrapped in liposomes.
摘要
就所产生的免疫反应而言，对给兔子施用抗原的三种方式进行了比较。抗原以溶液形式游离施用、包裹于脂质体中施用或在溶液中游离但与空脂质体一起施用。当脂质体材料与游离抗原一起注射时显示出佐剂活性，但当抗原包裹于脂质体中注射时发现佐剂效应要强得多。
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