Hong P H, Jampol L M, Dodwell D G, Hrisomalos N F, Lyon A T
Department of Ophthalmology, Northwestern University Medical School, Chicago, Ill., USA.
Arch Ophthalmol. 1997 Aug;115(8):1007-13. doi: 10.1001/archopht.1997.01100160177006.
To report a previously undescribed clinical entity involving an unusual inflammatory lesion of the choroid.
Six young, healthy patients experienced acute unilateral visual loss secondary to unifocal choroiditis in the macula.
All patients exhibited a solitary, elevated, yellow-white active focus of choroiditis with overlying subretinal fluid and in some cases subretinal hemorrhaging. The lesions were approximately 1 disc diameter in size and, on follow-up, showed minimal growth, then gradual resolution of the subretinal fluid. No other signs of ocular inflammation were noted, except in 1 patient who had anterior chamber and vitreous inflammation. In the 3 patients with prolonged follow-up, elevated white plaquelike lesions persisted with little change over time. Relapses were seen, and some permanent visual loss occurred in 1 of the 3 patients. Systemic evaluations revealed no definitive etiology.
To our knowledge, these patients exhibit an undescribed clinical entity, separable from previously established choroidal disorders. The cause of the lesions remains uncertain. We call this entity "unifocal helioid choroiditis."
报告一种此前未被描述的临床病症，其涉及脉络膜的一种罕见炎症性病变。
6名年轻健康患者因黄斑区单灶性脉络膜炎继发急性单侧视力丧失。
所有患者均表现为一个孤立的、隆起的、黄白色脉络膜炎活动病灶，伴有视网膜下液，部分病例伴有视网膜下出血。病灶大小约为1个视盘直径，随访时显示生长极小，随后视网膜下液逐渐消退。除1例患者有前房和玻璃体炎症外未发现其他眼部炎症迹象。在3例随访时间较长的患者中，白色斑块样隆起病灶持续存在，随时间变化很小。出现了复发情况，3例患者中有1例出现了永久性视力丧失。全身评估未发现明确病因。
据我们所知，这些患者表现出一种未被描述的临床病症，与先前已确定的脉络膜疾病不同。病变原因仍不确定。我们将这种病症称为“单灶性类向日葵脉络膜炎”。
