Starzl T E, Demetris A J, Murase N, Trucco M, Thomson A W, Rao A S, Fung J J
Pittsburgh Transplantation Institute, Pennsylvania, USA.
Curr Opin Nephrol Hypertens. 1997 May;6(3):292-8. doi: 10.1097/00041552-199705000-00015.
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft. Here, we describe how this hematolymphopoietic chimerism provides an important framework for interpretation of post-transplant phenomena and for initiation of therapeutically oriented transplantation research.
最近的证据表明，过客白细胞在器官移植后迁移并产生持续的嵌合现象，这对于同种异体移植物的持续存活至关重要。在此，我们描述了这种血液淋巴造血嵌合现象如何为解释移植后现象以及启动以治疗为导向的移植研究提供重要框架。
