Delevaux I, Hoen B, Selton-Suty C, Canton P
Service de Maladies Infectieuses et Tropicales, CHU de Nancy, Hôpitaux, Brabois, Vandoeuvre, France.
Mayo Clin Proc. 1997 Sep;72(9):848-50. doi: 10.4065/72.9.848.
Congestive cardiomyopathy is a highly unusual complication of Wegener's granulomatosis. In this report, we describe a 37-year-old man with histologically proven Wegener's granulomatosis who had two episodes of severe hypokinetic cardiomyopathy that responded well to cyclophosphamide. The theory that cardiomyopathy might be related to cardiac involvement in Wegener's granulomatosis and the beneficial effect of cyclophosphamide in this condition are discussed.
充血性心肌病是韦格纳肉芽肿极为罕见的并发症。在本报告中,我们描述了一名37岁经组织学证实患有韦格纳肉芽肿的男性,他曾两次发作严重的低动力性心肌病,对环磷酰胺反应良好。文中讨论了心肌病可能与韦格纳肉芽肿累及心脏有关的理论,以及环磷酰胺在此种情况下的有益作用。