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古巴哈瓦那呼吸道合胞病毒(A亚组)疫情的单克隆抗体及限制性酶切图谱分析(N基因)分子特征

Molecular characterization of an outbreak of respiratory syncytial virus (subgroup A) in Havana, Cuba, by monoclonal antibodies and restriction mapping (N gene).

作者信息

Valdivia A, Chacón D, Savón C, Oropesa S, Sarmiento L, Valdes O, Otero A, Rosario D, Goyenechea A

机构信息

Instituto de Medicina Tropical Pedro Kouri, Havana, Cuba.

出版信息

Clin Diagn Lab Immunol. 1997 Sep;4(5):633-4. doi: 10.1128/cdli.4.5.633-634.1997.

Abstract

Twenty-one respiratory syncytial virus (RSV) strains isolated from one outbreak in Havana, Cuba (1994 to 1995), were analyzed to determine their relatedness. All isolated strains were classified as subgroup A by monoclonal antibodies. Of 21 RSV strains examined, 20 were classified as having restriction pattern NP4 and only 1 was classified as having restriction pattern NP5.

摘要

对从古巴哈瓦那一次疫情(1994年至1995年)中分离出的21株呼吸道合胞病毒(RSV)进行了分析,以确定它们之间的亲缘关系。通过单克隆抗体将所有分离出的毒株归类为A亚组。在检测的21株RSV毒株中,20株被归类为具有NP4限制性图谱,只有1株被归类为具有NP5限制性图谱。

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