一种新抗生素——侧孢霉素的分离。芽孢杆菌属抗生素的研究。第十三部分。
Isolation of a new antibiotic, laterosporamine. Studies on antibiotics from the genus Bacillus. XIII.
作者信息
Shoji J, Sakazaki R, Wakisaka Y, Koizumi K, Mayama M
出版信息
J Antibiot (Tokyo). 1976 Apr;29(4):390-3. doi: 10.7164/antibiotics.29.390.
PMID:931807
Abstract
A new antibiotic, named laterosporamine, was isolated from the culture broth of Bacillus laterosporus 340-19. The antibiotic is active against Gram-positive and Gram-negative bacteria in vitro and in vivo. It is a water-soluble basic substance, positive to ninhydrin, SAKAGUCHI'S and DRAGENDORFF'S reagents. A non-peptidic structure with an approximate empirical formula C17H35N7O4 was suggested.
摘要
一种名为侧孢菌素的新型抗生素，是从侧孢芽孢杆菌340 - 19的培养液中分离出来的。该抗生素在体外和体内对革兰氏阳性菌和革兰氏阴性菌均有活性。它是一种水溶性碱性物质，对茚三酮、坂口试剂和碘化铋钾试剂呈阳性反应。有人提出其具有近似经验式为C17H35N7O4的非肽结构。
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