文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

O'Connor W J, Summerill R A

J Physiol. 1976 Mar;256(1):81-91. doi: 10.1113/jphysiol.1976.sp011312.

The exogenous creatinine clearance of conscious dogs has been measured by a method in which no loading doses of water or saline were given. The urine volume was thus in the normal range, 0-1-0-3ml./min. 2. Under these conditions, the exogenous creatine clearance of fourteen dogs, measured 17 hr after a meal, was 2-74 ml./min kg-1+/-0-54 (s.d.). This is about 40% lower than values usually regarded as "normal." 3. A meal of meat, 10g/kg, increased exogenous creatinine clearance reflects an increase in glomerular filtration rate. Since this occurs with small doses of meat, increase in glomerular filtration may be important in normal renal function of dogs.

采用一种不给水或盐水负荷剂量的方法测量了清醒犬的外源性肌酐清除率。因此尿量处于正常范围，即0.1 - 0.3毫升/分钟。2. 在这些条件下，十四只犬在进食后17小时测量的外源性肌酸清除率为2.74毫升/分钟·千克-1 ± 0.54（标准差）。这比通常认为的“正常”值低约40%。3. 10克/千克的肉类进食量增加了外源性肌酐清除率，这反映了肾小球滤过率的增加。由于小剂量肉类即可出现这种情况，肾小球滤过增加在犬的正常肾功能中可能很重要。

O'Connor W J, Summerill R A

J Physiol. 1976 Mar;256(1):81-91. doi: 10.1113/jphysiol.1976.sp011312.

The exogenous creatinine clearance of conscious dogs has been measured by a method in which no loading doses of water or saline were given. The urine volume was thus in the normal range, 0-1-0-3ml./min. 2. Under these conditions, the exogenous creatine clearance of fourteen dogs, measured 17 hr after a meal, was 2-74 ml./min kg-1+/-0-54 (s.d.). This is about 40% lower than values usually regarded as "normal." 3. A meal of meat, 10g/kg, increased exogenous creatinine clearance reflects an increase in glomerular filtration rate. Since this occurs with small doses of meat, increase in glomerular filtration may be important in normal renal function of dogs.

采用一种不给水或盐水负荷剂量的方法测量了清醒犬的外源性肌酐清除率。因此尿量处于正常范围，即0.1 - 0.3毫升/分钟。2. 在这些条件下，十四只犬在进食后17小时测量的外源性肌酸清除率为2.74毫升/分钟·千克-1 ± 0.54（标准差）。这比通常认为的“正常”值低约40%。3. 10克/千克的肉类进食量增加了外源性肌酐清除率，这反映了肾小球滤过率的增加。由于小剂量肉类即可出现这种情况，肾小球滤过增加在犬的正常肾功能中可能很重要。