Sargent J D, Bailey A, Simon P, Blake M, Dalton M A
Department of Pediatrics, Dartmouth Medical School, Hanover, New Hampshire, USA.
Environ Res. 1997;74(2):159-68. doi: 10.1006/enrs.1997.3755.
There has been increasing interest in a targeted approach to the screening and prevention of lead exposure in children. Targeted screening requires an understanding of variation in lead exposure in individual children or by region. In order to better understand variation by region, we studied Rhode Island lead poisoning screening data, examining average lead exposure to children living in 136 Providence County census tracts (CTs). The study population included 17,956 children aged 59 months and under, who were screened between May 1, 1992, and April 30, 1993. We evaluated the relationship between the percentage of children with blood lead > or = 10 micrograms/dL (pe10) and sociodemographic and housing characteristics, derived from United States 1990 Census data, of these CTs. CT descriptors included population density, percentage of households receiving public assistance income, median per capita income, percentage of households female headed, percentage of houses owner occupied, percentage of houses built before 1950, percentage of houses vacant, percentage of population Black, percentage of recent immigrants, and intraurban mobility. On average, 109 children were screened in each census tract; mean screening rate was 44%. There was wide variation in average lead exposure among census tracts, with pe10 ranging from 3 to 60% of screened children (mean 27%). Individual census variables explained between 24 and 67% of the variance in pe10 among CTs. A multiple regression model including percentage screened, percentage of households receiving public assistance, percentage of houses built before 1950, In (percentage of houses vacant), and percentage of recent immigrants explained 83% of variance in pe10. The percentage of houses built before 1950, a variable which models the presence of lead paint in old houses, displayed the largest adjusted effect on pe10 over the range observed for that variable in RI CTs. The percentage of houses vacant was also a highly significant and robust predictor; we suggest that vacancy is an ecological marker for the deterioration of leadbased paint, with higher vacancy neighborhoods containing houses in poorer condition. In Rhode Island, census tracts with high vacancy rates also have high rates of recent immigration, making immigrant groups vulnerable to lead exposure. Small-areas analysis may be useful in directing resources to high risk areas, explaining the sociocultural forces which produce such exposure and analyzing the effects of housing policy over time in states with high screening penetration.
针对儿童铅暴露的筛查和预防,采用靶向方法的关注度日益增加。靶向筛查需要了解个体儿童或不同地区铅暴露的差异。为了更好地了解地区差异,我们研究了罗德岛州铅中毒筛查数据,调查了普罗维登斯县136个普查区(CT)内儿童的平均铅暴露情况。研究人群包括17956名59个月及以下的儿童,他们在1992年5月1日至1993年4月30日期间接受了筛查。我们评估了血铅水平≥10微克/分升(pe10)的儿童百分比与这些普查区根据1990年美国人口普查数据得出的社会人口统计学和住房特征之间的关系。普查区描述指标包括人口密度、接受公共援助收入的家庭百分比、人均收入中位数、女性户主家庭百分比、自有住房百分比、1950年前建造的房屋百分比、空置房屋百分比、黑人人口百分比、新移民百分比以及市内流动性。平均而言,每个普查区筛查了109名儿童;平均筛查率为44%。普查区之间的平均铅暴露差异很大,pe10在筛查儿童中的比例从3%到60%不等(平均为27%)。各个普查变量解释了普查区之间pe10方差的24%至67%。一个多元回归模型,包括筛查百分比、接受公共援助的家庭百分比、1950年前建造的房屋百分比、ln(空置房屋百分比)和新移民百分比,解释了pe10方差的83%。1950年前建造的房屋百分比,这个变量可反映旧房屋中含铅油漆的存在情况,在罗德岛州普查区该变量观察范围内,对pe10显示出最大的调整效应。空置房屋百分比也是一个高度显著且稳健的预测指标;我们认为空置是含铅油漆恶化的一个生态标志,空置率较高的社区房屋状况较差。在罗德岛州,空置率高的普查区新移民率也高,这使得移民群体易受铅暴露影响。小区域分析可能有助于将资源导向高风险地区,解释导致此类暴露的社会文化因素,并分析在筛查普及率高的州住房政策随时间产生的影响。