• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

溃疡性结肠炎和克罗恩病的疾病活动度

The disease activity of ulcerative colitis and Crohn's disease.

作者信息

Talstad I, Gjone E

出版信息

Scand J Gastroenterol. 1976;11(4):403-8.

PMID:935802
Abstract

The disease activity in ulcerative colitis and Crohn's disease was studied. Parameters found to reflect the disease activity were given scores from 1 to 4. The score obtained by a patient compared with the maximum scores gives the percentage disease activity. The regressions between the percentage disease activity and the ESR in ulcerative colitis and Crohn's disease were r=0.68 (p less than 0.001) and r=0.48 (p less than 0.001), respectively. The different activity parameters have different time response curves explaining the occasional slight correlation. The percentage disease activity represents the mean activity of the different parameters at a given time. It is proposed to define slight, moderate, and severe ulcerative colitis or Crohn's disease as percentage disease activity of less than 30, 30-70 and greater than 70 per cent, respectively.

摘要

对溃疡性结肠炎和克罗恩病的疾病活动情况进行了研究。发现反映疾病活动的参数被赋予1至4分。患者获得的分数与最高分相比得出疾病活动百分比。溃疡性结肠炎和克罗恩病中疾病活动百分比与红细胞沉降率(ESR)之间的回归系数分别为r = 0.68(p < 0.001)和r = 0.48(p < 0.001)。不同的活动参数具有不同的时间反应曲线,这解释了偶尔出现的轻微相关性。疾病活动百分比代表给定时间不同参数的平均活动情况。建议将轻度、中度和重度溃疡性结肠炎或克罗恩病分别定义为疾病活动百分比低于30%、30%-70%和高于70%。

相似文献

1
The disease activity of ulcerative colitis and Crohn's disease.溃疡性结肠炎和克罗恩病的疾病活动度
Scand J Gastroenterol. 1976;11(4):403-8.
2
Plasma levels of endothelin-1 in patients with Crohn's disease and ulcerative colitis.克罗恩病和溃疡性结肠炎患者血浆内皮素-1水平
Ital J Gastroenterol Hepatol. 1998 Jun;30(3):266-9.
3
Inflammatory mediators and acute phase proteins in patients with Crohn's disease and ulcerative colitis.克罗恩病和溃疡性结肠炎患者体内的炎症介质与急性期蛋白
Hepatogastroenterology. 1997 Jan-Feb;44(13):90-107.
4
Unfractioned heparin in the therapy of patients with highly active inflammatory bowel disease.普通肝素在高活性炎症性肠病患者治疗中的应用
Am J Gastroenterol. 1999 Jun;94(6):1551-5. doi: 10.1111/j.1572-0241.1999.01143.x.
5
Direct hospital costs for patients with inflammatory bowel disease in a Canadian tertiary care university hospital.加拿大一所三级护理大学医院中炎症性肠病患者的直接住院费用。
Am J Gastroenterol. 2000 Mar;95(3):677-83. doi: 10.1111/j.1572-0241.2000.01845.x.
6
An investigation into the validity of the present classification of inflammatory bowel disease.对炎症性肠病现有分类有效性的调查。
Q J Med. 1985 Feb;54(214):183-90.
7
[Value of C-reactive protein in the evaluation of activity in ulcerative colitis and Crohn's disease].[C反应蛋白在溃疡性结肠炎和克罗恩病活动度评估中的价值]
Lijec Vjesn. 1990 Sep-Oct;112(9-10):281-4.
8
C-reactive protein: a predictive factor and marker of inflammation in inflammatory bowel disease. Results from a prospective population-based study.C反应蛋白:炎症性肠病中炎症的预测因子和标志物。一项基于人群的前瞻性研究结果
Gut. 2008 Nov;57(11):1518-23. doi: 10.1136/gut.2007.146357. Epub 2008 Jun 19.
9
Serum inhibitors of leukocyte chemotaxis in Crohn's disease and ulcerative colitis.克罗恩病和溃疡性结肠炎中白细胞趋化性的血清抑制剂
Gastroenterology. 1982 Jun;82(6):1327-34.
10
Identification of a prodromal period in Crohn's disease but not ulcerative colitis.克罗恩病前驱期的识别,但溃疡性结肠炎无此情况。
Am J Gastroenterol. 2000 Dec;95(12):3458-62. doi: 10.1111/j.1572-0241.2000.03361.x.

引用本文的文献

1
Disease monitoring in inflammatory bowel disease.炎症性肠病的疾病监测
World J Gastroenterol. 2015 Oct 28;21(40):11246-59. doi: 10.3748/wjg.v21.i40.11246.
2
Characterization of Serum Cytokine Profile in Predominantly Colonic Inflammatory Bowel Disease to Delineate Ulcerative and Crohn's Colitides.以区分溃疡性结肠炎和克罗恩结肠炎为目的的主要累及结肠的炎症性肠病血清细胞因子谱特征分析
Clin Med Insights Gastroenterol. 2015 May 6;8:29-44. doi: 10.4137/CGast.S20612. eCollection 2015.
3
Plasma osteopontin predicts inflammatory bowel disease activities.
血浆骨桥蛋白可预测炎症性肠病的活动情况。
Int Surg. 2015 Jan;100(1):38-43. doi: 10.9738/INTSURG-D-13-00160.1.
4
Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis.评估克罗恩病和溃疡性结肠炎的炎症活动度。
World J Gastroenterol. 2012 Mar 7;18(9):872-81. doi: 10.3748/wjg.v18.i9.872.
5
CRP correlates with clinical score in ulcerative colitis but not in Crohn's disease.CRP与溃疡性结肠炎的临床评分相关,但与克罗恩病无关。
Dig Dis Sci. 2007 Sep;52(9):2063-8. doi: 10.1007/s10620-006-9691-2. Epub 2007 Apr 11.
6
Activation of plasma contact and coagulation systems and neutrophils in the active phase of ulcerative colitis.溃疡性结肠炎活动期血浆接触和凝血系统及中性粒细胞的激活。
Dig Dis Sci. 1997 Nov;42(11):2356-66. doi: 10.1023/a:1018891323205.
7
Quantification of disease activity in Crohn's disease by computer analysis of Tc-99m hexamethyl propylene amine oxime (HMPAO) labelled leucocyte images.通过计算机分析锝-99m六甲基丙烯胺肟(HMPAO)标记的白细胞图像对克罗恩病的疾病活动进行定量分析。
Gut. 1993 Jan;34(1):68-74. doi: 10.1136/gut.34.1.68.
8
Faecal diversion for Crohn's colitis: a model to study the role of the faecal stream in the inflammatory process.克罗恩病性结肠炎的粪便转流:一种研究粪流在炎症过程中作用的模型。
Gut. 1994 Feb;35(2):236-42. doi: 10.1136/gut.35.2.236.
9
Anti-neutrophil cytoplasmic antibodies (ANCA) in inflammatory bowel disease: characterization and clinical correlates.炎症性肠病中的抗中性粒细胞胞浆抗体(ANCA):特征及临床相关性
Clin Exp Immunol. 1994 Mar;95(3):490-7. doi: 10.1111/j.1365-2249.1994.tb07024.x.
10
Colonoscopy of acute colitis. A safe and reliable tool for assessment of severity.急性结肠炎的结肠镜检查:一种评估严重程度的安全可靠工具。
Dig Dis Sci. 1994 Jul;39(7):1550-7. doi: 10.1007/BF02088063.