来自长叶黄杨的新型甾体生物碱。

New steroidal alkaloids from Buxus longifolia.

作者信息

Noor-e-ain F, Choudhary M I, Parveen Z, Türköz S, Sener B

机构信息

H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan. att@hejfirst%uunet.uu.net

出版信息

J Nat Prod. 1997 Oct;60(10):976-81. doi: 10.1021/np970207e.

DOI:10.1021/np970207e

PMID:9358638

Abstract

Four new steroidal alkaloids, (+)-cyclovirobuxeine F (1), N-benzoyl-O-acetylbuxalongifoline (2), buxasamarine (3), and (+)-cyclobuxamidine (4), along with two known steroidal bases, 16 alpha-acetoxybuxabenzamidienine (5) and trans-cyclosuffrobuxinine (6), were isolated from the leaves of Buxus longifolia. The alkaloids 1-4 showed significant antibacterial activity.

摘要

从长叶黄杨的叶子中分离出四种新的甾体生物碱，即(+)-环维黄杨星F（1）、N-苯甲酰基-O-乙酰基黄杨长碱（2）、黄杨苦素（3）和(+)-环黄杨酰胺（4），以及两种已知的甾体碱，16α-乙酰氧基黄杨苯甲酰胺（5）和反式环苏夫黄杨宁（6）。生物碱1-4表现出显著的抗菌活性。