Bix B C, Glosser G, Holmes W, Ballas C, Meritz M, Hutelmyer C, Turner J
Department of Medicine, Graduate Hospital, Philadelphia, Pennsylvania 19146, USA.
J Int Neuropsychol Soc. 1995 Nov;1(6):581-8. doi: 10.1017/s1355617700000722.
Neuropsychological impairment and DSM-III-R Axis I psychiatric diagnoses were evaluated in a heterogenous group of HIV seropositive individuals and seronegative individuals with similar risk factors for HIV infection. Neuropsychological and psychiatric disorders were common in the HIV seropositive group, but there were no relationships between these two aspects of neuropsychiatric dysfunction in seropositive patients. Results indicate that psychiatric disorders in HIV seropositive individuals tend to predate infection and decrease over time following knowledge of seroconversion, suggesting that they are primarily a function of psychosocial factors. Neuropsychological disorders are specific to HIV seropositive patients and tend to increase over time following seroconversion, suggesting that they are due to neurological effects of HIV-infection.
在一组感染HIV风险因素相似的HIV血清阳性个体和血清阴性个体中，对神经心理损伤和《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）轴I精神疾病诊断进行了评估。神经心理和精神疾病在HIV血清阳性组中很常见，但在血清阳性患者中，这两个神经精神功能障碍方面之间没有关联。结果表明，HIV血清阳性个体中的精神疾病往往在感染之前就已存在，并在血清转换确诊后随时间推移而减少，这表明它们主要是社会心理因素的作用。神经心理障碍是HIV血清阳性患者所特有的，并且在血清转换后往往随时间增加，这表明它们是由HIV感染的神经学效应所致。
