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胰腺黏液性囊性肿瘤的“卵巢型”间质表达平滑肌表型。

'Ovarian-type' stroma of pancreatic mucinous cystic tumor expresses smooth muscle phenotype.

作者信息

Fukushima N, Mukai K

出版信息

Pathol Int. 1997 Nov;47(11):806-8. doi: 10.1111/j.1440-1827.1997.tb04462.x.

DOI:10.1111/j.1440-1827.1997.tb04462.x
PMID:9413043
Abstract

'Ovarian-type' stroma of nine mucinous cystic tumors (MCT) of the pancreas, six cystadenomas and three cystadenocarcinomas, were studied immunohistochemically. Most of the spindle cells of the 'ovarian-type' stroma were positive for smooth muscle actin and desmin, but were negative for S-100 protein, cytochrome P450 19 and CD34. Similar stroma with smooth muscle differentiation has been described in hepatobiliary MCT. Embryologic similarity between the pancreas and liver suggests a closely related origin of MCT in both organs.

摘要

对9例胰腺黏液性囊性肿瘤(MCT)(6例囊腺瘤和3例囊腺癌)的“卵巢型”间质进行了免疫组织化学研究。“卵巢型”间质的大多数梭形细胞平滑肌肌动蛋白和结蛋白呈阳性,但S-100蛋白、细胞色素P450 19和CD34呈阴性。在肝胆MCT中也描述过具有平滑肌分化的类似间质。胰腺和肝脏之间的胚胎学相似性提示这两个器官中MCT的起源密切相关。

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'Ovarian-type' stroma of pancreatic mucinous cystic tumor expresses smooth muscle phenotype.胰腺黏液性囊性肿瘤的“卵巢型”间质表达平滑肌表型。
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引用本文的文献

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World J Surg Oncol. 2009 May 19;7:47. doi: 10.1186/1477-7819-7-47.
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Mucinous cystic tumour of the pancreas presenting with acute pancreatitis.胰腺黏液性囊性肿瘤伴发急性胰腺炎。
HPB (Oxford). 2001;3(4):271-3. doi: 10.1080/136518201753335782.
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Morphogenesis of pancreatic cancer: role of pancreatic intraepithelial neoplasia (PanINs).胰腺癌的形态发生:胰腺上皮内瘤变(PanINs)的作用。
Langenbecks Arch Surg. 2008 Jul;393(4):561-70. doi: 10.1007/s00423-008-0282-x. Epub 2008 Feb 19.
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Mucinous cystic neoplasm of the pancreas with ovarian-type stroma arising in the head of the pancreas: case report and review of the literature.胰腺头部发生的伴有卵巢型间质的胰腺黏液性囊性肿瘤:病例报告及文献复习
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Mucinous cystadenoma of the pancreas with predominant stroma creating a solid tumor.胰腺黏液性囊腺瘤,以形成实性肿瘤的间质为主。
World J Surg Oncol. 2005 Sep 7;3:59. doi: 10.1186/1477-7819-3-59.