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基层医疗中肠易激综合征患者与门诊肠易激综合征患者真的存在差异吗?

Do patients with irritable bowel syndrome in primary care really differ from outpatients with irritable bowel syndrome?

作者信息

van der Horst H E, van Dulmen A M, Schellevis F G, van Eijk J T, Fennis J F, Bleijenberg G

机构信息

Department of General Practice, Nursing Home and Social Medicine, Vrije Universiteit, Amsterdam, The Netherlands.

出版信息

Gut. 1997 Nov;41(5):669-74. doi: 10.1136/gut.41.5.669.

Abstract

BACKGROUND

Little is known about the comparability of outpatients with irritable bowel syndrome (IBS) and patients with IBS in primary care with regard to severity of complaints, perceived limitations, other aspects of the complaints, and sex differences.

AIMS

To compare outpatients with IBS with primary care patients with IBS.

PATIENTS

One hundred and nine patients with IBS were recruited from general practices in Amsterdam and 86 patients with IBS were recruited from the outpatient clinic of the Department of Internal Medicine of the University Hospital in Nijmegen.

METHODS

Each patient completed a questionnaire on demographic variables, abdominal complaints, related complaints, and attributed causes of their abdominal complaints. The scores of the two groups were compared by univariate and multivariate analysis.

RESULTS

The outpatient group contained significantly more men, reported more severe abdominal pain, more frequent complaints, more interference with daily activities, and a higher degree of avoidance of activities (p < 0.01) than the primary care group. When each sex was analysed separately, these differences remained for female (p < 0.01) but not for male patients. Outpatients were more likely to attribute their complaints to somatic causes (p < 0.01), whereas primary care patients were more likely to attribute their complaints to stress (p < 0.01) or their agitated way of life (p < 0.05). Multivariate analysis showed that a high severity score, a large number of additional complaints, and a low score on the stress attribution were important determinants for being in the outpatient group.

CONCLUSIONS

Female outpatients consider their complaints to be more serious and interfering than do patients with IBS in primary care. Male outpatients were comparable to primary care patients with IBS. More research needs to be done into sex specific differences in IBS and into the factors that influence the decision to refer a patient with IBS.

摘要

背景

关于肠易激综合征(IBS)门诊患者与基层医疗中IBS患者在症状严重程度、感知到的限制、症状的其他方面以及性别差异方面的可比性,人们了解甚少。

目的

比较IBS门诊患者与基层医疗IBS患者。

患者

从阿姆斯特丹的全科诊所招募了109例IBS患者,从奈梅亨大学医院内科门诊招募了86例IBS患者。

方法

每位患者完成一份关于人口统计学变量、腹部症状、相关症状以及腹部症状归因原因的问卷。通过单因素和多因素分析比较两组的得分。

结果

门诊患者组男性明显更多,报告的腹痛更严重、症状更频繁、对日常活动的干扰更大以及活动回避程度更高(p<0.01),高于基层医疗组。当分别分析每种性别时,这些差异在女性中仍然存在(p<0.01),但在男性患者中不存在。门诊患者更倾向于将其症状归因于躯体原因(p<0.01),而基层医疗患者更倾向于将其症状归因于压力(p<0.01)或他们烦躁的生活方式(p<0.05)。多因素分析表明,高严重程度得分、大量额外症状以及压力归因得分低是门诊患者组的重要决定因素。

结论

女性门诊患者认为她们的症状比基层医疗中的IBS患者更严重且干扰更大。男性门诊患者与基层医疗IBS患者相当。需要对IBS中的性别特异性差异以及影响IBS患者转诊决定的因素进行更多研究。

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