Scott D A, Coulter W A, Lamey P J
School of Clinical Dentistry, Queen's University of Belfast, N. Ireland.
J Oral Pathol Med. 1997 Nov;26(10):441-7. doi: 10.1111/j.1600-0714.1997.tb00012.x.
Herpes simplex virus type 1 (HSV-1) and, to a lesser extent, type 2 (HSV-2) are the aetiological agents of recrudescent herpes labialis (RHL). The available literature on patterns of HSV-1 shedding into the oral cavity at the prodromal stage of disease, during recrudescences and also during asymptomatic periods, is reviewed, as are the potential sources of virus and the known trigger factors leading to viral reactivation. Attention is given to the methodologies in use for the detection of HSV-1 and the relevance to the risk of cross-infection in surgery. This review also discusses the increase in incidence of HSV-1 genital infections and the significance of salivary inhibitors of the herpes simplex type 1 virus.
1型单纯疱疹病毒（HSV-1），在较小程度上还有2型单纯疱疹病毒（HSV-2），是复发性唇疱疹（RHL）的病原体。本文综述了关于疾病前驱期、复发期以及无症状期HSV-1在口腔中脱落模式的现有文献，以及病毒的潜在来源和导致病毒再激活的已知触发因素。文中还关注了用于检测HSV-1的方法及其与手术中交叉感染风险的相关性。本综述还讨论了HSV-1生殖器感染发病率的增加以及1型单纯疱疹病毒唾液抑制剂的意义。
