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Studies of chemotaxis of lymphocytes.

作者信息

Wilkinson P C, Russell R J, Pumphrey R S, Sless F, Parrott D M

出版信息

Agents Actions. 1976 Feb;6(1-3):243-7. doi: 10.1007/BF01972215.

DOI:10.1007/BF01972215
PMID:941797
Abstract

Lymphoblasts migrate into filters towards chemoattractants in vitro. Human lymphoblasts maintained in continuous culture and mouse lymphoblasts from unsensitized lymph nodes show chemotactic responses and migrate towards the same chemotactic factors as neutrophils and macrophages, namely activated plasma, casein, denatured serum albumin, oxazolone. On the other hand, mouse lymphoblasts from oxazolone-sensitized lymph nodes show considerable random migration and chemokinesis but not chemotaxis. The migration of lymphoblasts to these agents appears not to be antigen-specific. These migratory properties of lymphoblasts are probably relevant to their migration into inflammatory sites in vivo.

摘要

相似文献

1
Studies of chemotaxis of lymphocytes.
Agents Actions. 1976 Feb;6(1-3):243-7. doi: 10.1007/BF01972215.
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引用本文的文献

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Stereospecific chemoattraction of lymphoblastic cells by gradients of lysophosphatidylcholine.溶血磷脂酰胆碱梯度对淋巴细胞的立体特异性化学吸引作用。
Proc Natl Acad Sci U S A. 1982 May;79(10):3285-9. doi: 10.1073/pnas.79.10.3285.
2
Factors which determine the accumulation of immunoblasts in gut and skin.决定免疫母细胞在肠道和皮肤中聚集的因素。
Agents Actions. 1976 Feb;6(1-3):32-9. doi: 10.1007/BF01972183.
3
Chemotaxis of mitogen-activated human lymphocytes and the effects of membrane-active enzymes.有丝分裂原激活的人淋巴细胞的趋化作用及膜活性酶的影响。

本文引用的文献

1
The movement of lymphocytes.淋巴细胞的运动。
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Induction and recall in contact sensivitity. Changes in skin and draining lymph nodes of intact and thymectomized mice.接触敏感性中的诱导和回忆。完整小鼠和胸腺切除小鼠的皮肤及引流淋巴结的变化。
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Chemoattractants of leukocytes, with special reference to lymphocytes.白细胞趋化因子，特别涉及淋巴细胞
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Physiology of granulocyte locomotion and its relation to defects of chemotaxis: a review.粒细胞运动生理学及其与趋化性缺陷的关系：综述
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Contact sensitivity in the mouse. XI. Movement of T blasts in the draining lymph nodes to sites of inflammation.小鼠中的接触敏感性。十一、引流淋巴结中T母细胞向炎症部位的移动。
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Nonspecific entry of thoracic duct immunoblasts into intradermal foci of antigens.胸导管免疫母细胞非特异性进入真皮内抗原灶。
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Human lymphoblastoid cell lines. 3. Co-cultivation technique for establishment of new lines.
J Natl Cancer Inst. 1972 Mar;48(3):623-8.
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The mediator of cellular immunity. VII. Localization of sensitized lymphocytes in inflammatory exudates.细胞免疫的介质。VII. 致敏淋巴细胞在炎性渗出物中的定位。
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