Davies G R, Rampton D S
Centre for Digestive Diseases, The General Infirmary, Leeds, UK.
Eur J Gastroenterol Hepatol. 1997 Nov;9(11):1033-44. doi: 10.1097/00042737-199711000-00003.
This paper contains a brief review of the metabolism and physiological actions of eicosanoids, with a discussion of the potential clinical implications of disturbances in eicosanoid metabolism, particularly in NSAID-induced upper gastrointestinal damage and inflammatory bowel disease. There follows a summary of current evidence for the role of eicosanoids in the pathogenesis of colorectal neoplasia.
