免疫活性宿主外周血单个核细胞在细胞培养中的细胞因子产生。
Cytokine production in cell culture by peripheral blood mononuclear cells from immunocompetent hosts.
作者信息
Katial R K, Sachanandani D, Pinney C, Lieberman M M
机构信息
Department of Allergy and Immunology, Walter Reed Army Medical Center, Washington, DC 20307, USA.
出版信息
Clin Diagn Lab Immunol. 1998 Jan;5(1):78-81. doi: 10.1128/CDLI.5.1.78-81.1998.
Abstract
The production of interleukin 2 (IL-2) gamma interferon, IL-4, tumor necrosis factor alpha (TNF-alpha), TNF-beta, IL-5, and IL-10 in vitro by peripheral blood mononuclear cells cultured from healthy immunocompetent subjects after mitogen stimulation was determined. The mitogens used were concanavalin A, phytohemagglutinin, pokeweed mitogen, and Staphylococcus aureus Cowen. The results obtained provide a normal range for the production of these cytokines under specified conditions in vitro.
摘要
测定了来自健康免疫活性受试者的外周血单个核细胞在有丝分裂原刺激后体外产生白细胞介素2（IL-2）、γ干扰素、IL-4、肿瘤坏死因子α（TNF-α）、TNF-β、IL-5和IL-10的情况。所使用的有丝分裂原是刀豆球蛋白A、植物血凝素、商陆有丝分裂原和金黄色葡萄球菌考恩株。所获得的结果为这些细胞因子在特定体外条件下的产生提供了一个正常范围。
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