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肌萎缩侧索硬化症的前驱事件。

Antecedent events in amyotrophic lateral sclerosis.

作者信息

Felmus M T, Patten B M, Swanke L

出版信息

Neurology. 1976 Feb;26(2):167-72. doi: 10.1212/wnl.26.2.167.

DOI:10.1212/wnl.26.2.167
PMID:946326
Abstract

To identify antecedent events contributing to the development of amyotrophic lateral sclerosis, we studied 25 amyotrophic lateral sclerosis patients in whom we tabulated the incidence of factors previously associated with motor neuron disease and compared the incidences with those found in 25 hospitalized patients and 25 normal people. More amyotrophic lateral sclerosis patients reported exposure to lead and mercury, participation in athletics, and consumption of large quantities of milk. Exposure to lead and mercury, athletic participation, and milk ingestion are possible risk factors that may predispose to the development of amyotrophic lateral sclerosis.

摘要

为了确定导致肌萎缩侧索硬化症(ALS)发生的前驱事件,我们研究了25例肌萎缩侧索硬化症患者,将先前与运动神经元疾病相关的因素发生率制成表格,并将这些发生率与25例住院患者和25名正常人的发生率进行比较。更多的肌萎缩侧索硬化症患者报告有铅和汞暴露史、参加过体育运动以及大量饮用牛奶。铅和汞暴露、体育运动参与以及牛奶摄入可能是易患肌萎缩侧索硬化症的危险因素。

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1
Antecedent events in amyotrophic lateral sclerosis.肌萎缩侧索硬化症的前驱事件。
Neurology. 1976 Feb;26(2):167-72. doi: 10.1212/wnl.26.2.167.
2
Motor neuron disease and toxic metals.运动神经元病与有毒金属
Adv Neurol. 1982;36:201-31.
3
[A clinical evaluation of the inorganic mercurialism--its pathogenic relation to amyotrophic lateral sclerosis].[无机汞中毒的临床评估——其与肌萎缩侧索硬化症的致病关系]
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Heavy metals and trace elements in amyotrophic lateral sclerosis.肌萎缩侧索硬化症中的重金属和微量元素
Neurol Clin. 1987 Feb;5(1):43-60.
5
[On a case of saturnism associated with amyotrophic lateral sclerosis].[一例与肌萎缩侧索硬化症相关的铅中毒病例]
Med Lav. 1968 Oct;59(10):599-603.
6
Are environmental exposures to selenium, heavy metals, and pesticides risk factors for amyotrophic lateral sclerosis?环境暴露于硒、重金属和农药是否是肌萎缩侧索硬化症的危险因素?
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Trauma, axonal injury, and amyotrophic lateral sclerosis: a clinical correlate of a neuropharmacologic model.
Clin Neuropharmacol. 1995 Jun;18(3):273-6. doi: 10.1097/00002826-199506000-00008.
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Antecedent events in amyotrophic lateral sclerosis: do they influence clinical onset and progression?肌萎缩侧索硬化症的前驱事件:它们是否会影响临床发病和病情进展?
Neuroepidemiology. 1990;9(5):255-62. doi: 10.1159/000110782.
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Trauma and amyotrophic lateral sclerosis: a report of 78 patients.创伤与肌萎缩侧索硬化症:78例患者的报告
Acta Neurol Scand. 1987 Feb;75(2):145-50. doi: 10.1111/j.1600-0404.1987.tb07909.x.
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Antecedent trauma and amyotrophic lateral sclerosis in young adult men.年轻男性的既往创伤与肌萎缩侧索硬化症
Mil Med. 1993 Jan;158(1):55-7.

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Extracellular Vesicles as Potential Biomarkers in Amyotrophic Lateral Sclerosis.
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