Cho Z H, Chung S C, Jones J P, Park J B, Park H J, Lee H J, Wong E K, Min B I
Department of Radiological Sciences, Psychiatry, and Human Behavior, University of California, Irvine, CA 92697, USA.
Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2670-3. doi: 10.1073/pnas.95.5.2670.
A preliminary study of the correlation between acupuncture points (acupoints) for the treatment of eye disorders suggested by ancient Oriental literature and the corresponding brain localization for vision described by Western medicine was performed by using functional MRI (fMRI). The vision-related acupoint (VA1) is located in the lateral aspect of the foot, and when acupuncture stimulation is performed there, activation of occipital lobes is seen by fMRI. Stimulation of the eye by directly using light results in similar activation in the occipital lobes by fMRI. The experiment was conducted by using conventional checkerboard 8-Hz light-flash stimulation of the eye and observation of the time-course data. This was followed by stimulation of the VA1 by using the same time-course paradigm as visual light stimulation. Results obtained with 12 volunteers yielded very clean data and very close correlations between visual and acupuncture stimulation. We have also stimulated nonacupoints 2 to 5 cm away from the vision-related acupoints on the foot as a control, and activation in the occipital lobes was not observed. The results obtained demonstrate the correlation between activation of specific areas of brain cortices and corresponding acupoint stimulation predicted by ancient acupuncture literature.
通过功能磁共振成像(fMRI)对古代东方文献中所提及的治疗眼部疾病的穴位与西医所描述的视觉相关脑定位之间的相关性进行了初步研究。与视觉相关的穴位(VA1)位于足部外侧,当在此处进行针刺刺激时,fMRI可观察到枕叶的激活。直接用光刺激眼睛时,fMRI也可在枕叶观察到类似的激活。实验采用传统的棋盘格8赫兹闪光刺激眼睛,并观察时间进程数据。随后,采用与视觉光刺激相同的时间进程模式对VA1进行刺激。12名志愿者的实验结果产生了非常清晰的数据,且视觉刺激与针刺刺激之间的相关性非常密切。我们还刺激了足部与视觉相关穴位相距2至5厘米的非穴位作为对照,未观察到枕叶的激活。所获得的结果证明了大脑皮层特定区域的激活与古代针灸文献所预测的相应穴位刺激之间的相关性。