Ribonucleotide reductases in the twenty-first century.
作者信息
Stubbe J
机构信息
Departments of Chemistry and Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
出版信息
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2723-4. doi: 10.1073/pnas.95.6.2723.
Abstract
摘要
相似文献
1
Ribonucleotide reductases in the twenty-first century.21世纪的核糖核苷酸还原酶。
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2723-4. doi: 10.1073/pnas.95.6.2723.
2
Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase.用于研究I类核糖核苷酸还原酶中自由基反应的光谱学和理论方法。
Biol Chem. 2005 Oct;386(10):1007-22. doi: 10.1515/BC.2005.117.
3
The evolution of ribonucleotide reduction.核糖核苷酸还原的演变
Trends Biochem Sci. 1997 Mar;22(3):81-5. doi: 10.1016/s0968-0004(97)01003-7.
4
Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?I类核糖核苷酸还原酶中的自由基引发：远程质子耦合电子转移？
Chem Rev. 2003 Jun;103(6):2167-201. doi: 10.1021/cr020421u.
5
The evolution of ribonucleotide reduction revisited.核糖核苷酸还原的进化再探讨。
Trends Biochem Sci. 2001 Feb;26(2):93-9. doi: 10.1016/s0968-0004(00)01764-3.
6
Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study.铁锰蛋白的体外和体内金属化和非金属化：以 I 类核糖核苷酸还原酶为例。
Metallomics. 2012 Oct;4(10):1020-36. doi: 10.1039/c2mt20142a. Epub 2012 Sep 18.
7
Ribonucleotide reductases: the evolution of allosteric regulation.核糖核苷酸还原酶：变构调节的进化
Arch Biochem Biophys. 2002 Jan 15;397(2):149-55. doi: 10.1006/abbi.2001.2637.
8
Thiols in redox mechanism of ribonucleotide reductase.核糖核苷酸还原酶氧化还原机制中的硫醇
Methods Enzymol. 2002;348:1-21. doi: 10.1016/s0076-6879(02)48620-x.
9
Ribonucleotide reductases.核糖核苷酸还原酶
Annu Rev Biochem. 2006;75:681-706. doi: 10.1146/annurev.biochem.75.103004.142443.
10
Ribonucleotide reductases: substrate specificity by allostery.核苷酸还原酶：变构作用的底物特异性。
Biochem Biophys Res Commun. 2010 May 21;396(1):19-23. doi: 10.1016/j.bbrc.2010.02.108.
引用本文的文献
1
Protein-derived cofactors: chemical innovations expanding enzyme catalysis.蛋白质衍生的辅因子：拓展酶催化作用的化学创新
Chem Soc Rev. 2025 May 6;54(9):4502-4530. doi: 10.1039/d4cs00981a.
2
Conformational control over proton-coupled electron transfer in metalloenzymes.构象控制在金属酶中的质子耦合电子转移。
Nat Rev Chem. 2024 Oct;8(10):762-775. doi: 10.1038/s41570-024-00646-7. Epub 2024 Sep 2.
3
Maize LOST SUBSIDIARY CELL encoding a large subunit of ribonucleotide reductase is required for subsidiary cell development and plant growth.玉米 LOST SUBSIDIARY CELL 编码核苷酸还原酶大亚基，对于侧生细胞的发育和植物生长是必需的。
J Exp Bot. 2023 Aug 17;74(15):4449-4460. doi: 10.1093/jxb/erad153.
4
Radicals in Biology: Your Life Is in Their Hands.生物学中的自由基：你的生命掌握在它们手中。
J Am Chem Soc. 2021 Sep 1;143(34):13463-13472. doi: 10.1021/jacs.1c05952. Epub 2021 Aug 23.
5
In-Cell Characterization of the Stable Tyrosyl Radical in E. coli Ribonucleotide Reductase Using Advanced EPR Spectroscopy.使用先进的电子顺磁共振波谱技术对大肠杆菌核苷酸还原酶中稳定的酪氨酸自由基进行细胞内特性分析。
Angew Chem Int Ed Engl. 2021 Aug 23;60(35):19155-19161. doi: 10.1002/anie.202102914. Epub 2021 Jun 4.
6
Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets.核苷酸还原酶：结构、化学和代谢提示新的治疗靶点。
Annu Rev Biochem. 2020 Jun 20;89:45-75. doi: 10.1146/annurev-biochem-013118-111843.
7
Convergent allostery in ribonucleotide reductase.核苷酸还原酶的会聚变构。
Nat Commun. 2019 Jun 14;10(1):2653. doi: 10.1038/s41467-019-10568-4.
8
Ribonucleotide reductase subunit M2 as a novel target for clear-cell renal cell carcinoma.核糖核苷酸还原酶亚基M2作为肾透明细胞癌的新靶点。
Onco Targets Ther. 2019 Apr 30;12:3267-3275. doi: 10.2147/OTT.S196347. eCollection 2019.
9
ERK Inhibitor Enhances Everolimus Efficacy through the Attenuation of dNTP Pools in Renal Cell Carcinoma.ERK抑制剂通过降低肾细胞癌中的脱氧核苷酸三磷酸池增强依维莫司疗效。
Mol Ther Nucleic Acids. 2019 Mar 1;14:550-561. doi: 10.1016/j.omtn.2019.01.001. Epub 2019 Jan 10.
10
Properties of Site-Specifically Incorporated 3-Aminotyrosine in Proteins To Study Redox-Active Tyrosines: Escherichia coli Ribonucleotide Reductase as a Paradigm.用于研究氧化还原活性酪氨酸的蛋白质中位点特异性掺入的3-氨基酪氨酸的性质：以大肠杆菌核糖核苷酸还原酶为例
Biochemistry. 2018 Jun 19;57(24):3402-3415. doi: 10.1021/acs.biochem.8b00160. Epub 2018 Apr 17.
本文引用的文献
1
Raster3D: photorealistic molecular graphics.Raster3D：逼真的分子图形。
Methods Enzymol. 1997;277:505-24. doi: 10.1016/s0076-6879(97)77028-9.
2
3
A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J Biol Chem. 1997 Dec 12;272(50):31533-41. doi: 10.1074/jbc.272.50.31533.
4
B12-dependent ribonucleotide reductases from deeply rooted eubacteria are structurally related to the aerobic enzyme from Escherichia coli.来自根基深厚的真细菌的依赖维生素B12的核糖核苷酸还原酶在结构上与大肠杆菌的需氧酶相关。
Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13487-92. doi: 10.1073/pnas.94.25.13487.
5
Rnr4p, a novel ribonucleotide reductase small-subunit protein.Rnr4p，一种新型核糖核苷酸还原酶小亚基蛋白。
Mol Cell Biol. 1997 Oct;17(10):6114-21. doi: 10.1128/MCB.17.10.6114.
6
Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae.酿酒酵母中编码核糖核苷酸还原酶第二个必需小亚基的RNR4的鉴定。
Mol Cell Biol. 1997 Oct;17(10):6105-13. doi: 10.1128/MCB.17.10.6105.
7
Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.变构效应剂与核糖核苷酸还原酶蛋白R1的结合：活性位点半胱氨酸的还原促进底物结合。
Structure. 1997 Aug 15;5(8):1077-92. doi: 10.1016/s0969-2126(97)00259-1.
8
Role of ribonucleotide reductase and deoxynucleotide pools in the oxygen-dependent control of DNA replication in Ehrlich ascites cells.
Eur J Biochem. 1997 Mar 1;244(2):286-93. doi: 10.1111/j.1432-1033.1997.00286.x.
9
The evolution of ribonucleotide reduction.核糖核苷酸还原的演变
Trends Biochem Sci. 1997 Mar;22(3):81-5. doi: 10.1016/s0968-0004(97)01003-7.
10
Ribonucleotide reductase in the archaeon Pyrococcus furiosus: a critical enzyme in the evolution of DNA genomes?嗜热栖热菌中的核糖核苷酸还原酶：DNA基因组进化中的关键酶？
Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):475-8. doi: 10.1073/pnas.94.2.475.
Zotero 插件