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8-甲氧基补骨脂素光化学疗法治疗寻常型银屑病的技术经验

[Technical experience with 8-methoxypsoralen photochemotherapy in common psoriasis].

作者信息

Hofmann C, Plewig G, Braun-Falco O

出版信息

Hautarzt. 1976 Jun;27(6):277-85.

PMID:950302
Abstract

Photochemotherapy with 8-MOP und UV-A is a modality to treat psoriasis vulgaris successfully. Technical experiences with three types of machines, a horizontal box with Sylvania fluorescent lamps, a stand-up box, and a hand-foot-box with Osram fluorescent lamps are reported. Oral and topical 8-MOP applications are compared for these three types of boxes. Disadvantages of the oral or topical 8-MOP applications are compiled. Oral 8-MOP is superior to the topical treatment in both the stand-up and the horizontal box. The following technical features are discussed: Minimal phototoxic dose, photopigmentation index, radiation-dose, time increments during treatment, maintenance therapy, and UV-A meters.

摘要

用8-甲氧基补骨脂素(8-MOP)及紫外线A(UV-A)进行光化学疗法是一种成功治疗寻常型银屑病的方法。本文报告了使用三种不同机器的技术经验,这三种机器分别是配备ylvania荧光灯的卧式箱、立式箱以及配备欧司朗荧光灯的手足箱。对这三种箱子使用口服和外用8-MOP的情况进行了比较。汇总了口服或外用8-MOP的缺点。在立式箱和卧式箱中,口服8-MOP均优于局部治疗。讨论了以下技术特点:最小光毒剂量、光色素沉着指数、辐射剂量、治疗期间的时间增量、维持治疗以及UV-A测量仪。

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