Jordan D, Kermadi I, Rambaud C, Bouvier R, Dijoud F, Martin D, Kopp N
Anatomo-Pathologic Laboratory, Laënnec University, Lyon, France.
J Neural Transm (Vienna). 1997;104(10):1101-5. doi: 10.1007/BF01273322.
The precise distribution of substance P (SP) binding sites in the human brainstem was investigated in normal cases (3 fetuses and 24 new-borns) and in 9 cases of Sudden Infant Death Syndrome (SIDS) by in vitro quantitative autoradiography. We discussed the widely but uneven distribution of SP binding sites as regards to the role of SP in brainstem cardio-respiratory ontogenic control and its possible involvement in SIDS.
通过体外定量放射自显影技术，研究了正常情况（3例胎儿和24例新生儿）及9例婴儿猝死综合征（SIDS）病例中，P物质（SP）结合位点在人脑干中的精确分布。我们讨论了SP结合位点广泛但不均匀的分布情况，及其在脑干心肺发育控制中的作用，以及其可能与婴儿猝死综合征的关联。
