Fletcher A K, Weetman A P
University of Sheffield, Department of Medicine, Northern General Hospital, UK.
J Hum Hypertens. 1998 Feb;12(2):79-82. doi: 10.1038/sj.jhh.1000574.
Correction of the causes of secondary forms of hypertension usually restores blood pressure to normal. Hypothyroidism is a potentially important but overlooked cause of hypertension and restoration of euthyroidism with thyroxine therapy usually results in a substantial reduction in both systolic and diastolic blood pressure, especially in younger subjects. The mechanism of hypertension in hypothyroidism is not completely understood: changes in circulating catecholamines, their receptors and the renin-angiotensin-aldosterone system have all been implicated. Effective treatment with thyroxine is readily available and inexpensive.
纠正继发性高血压的病因通常可使血压恢复正常。甲状腺功能减退是高血压一个潜在的重要但被忽视的病因，用甲状腺素治疗使甲状腺功能恢复正常通常会导致收缩压和舒张压大幅降低，尤其是在年轻患者中。甲状腺功能减退时高血压的机制尚未完全明了：循环儿茶酚胺、其受体以及肾素 - 血管紧张素 - 醛固酮系统的变化均与之有关。甲状腺素的有效治疗容易获得且价格低廉。
