新型隐球菌灭活后的免疫佐剂作用。
Immunoadjuvant effect of inactivated Cryptococcus neoformans.
作者信息
Hubálek Z
机构信息
Institute of Landscape Ecology, Academy of Sciences, Brno, Czech Republic.
出版信息
Mycopathologia. 1997;139(1):19-21. doi: 10.1023/a:1006851714417.
PMID:9511233
Abstract
Cryptococcus neoformans disseminated into the central nervous system (CNS) of intraperitoneally inoculated adult ICR mice, but did not potentiate penetration of concurrently given Bhanja virus (Bunyaviridae) into the CNS. Likewise, Bhanja virus infection did not affect significantly the course of murine cryptococcosis. However, formalin-killed C. neoformans cells non-specifically increased production of antibodies against the virus infection in the animals.
摘要
新型隐球菌可扩散至经腹腔接种的成年ICR小鼠的中枢神经系统（CNS），但不会增强同时接种的班贾病毒（布尼亚病毒科）进入中枢神经系统的能力。同样，班贾病毒感染对小鼠隐球菌病的病程也没有显著影响。然而，经福尔马林灭活的新型隐球菌细胞可非特异性地增加动物体内针对病毒感染的抗体产生。
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