Bode G, Rothenbacher D, Brenner H, Adler G
Department of Internal Medicine I, University of Ulm, Ulm, Germany.
Pediatrics. 1998 Apr;101(4 Pt 1):634-7. doi: 10.1542/peds.101.4.634.
To determine the relation of Helicobacter pylori infection with gastrointestinal symptoms in a healthy population-based sample of children.
Population-based cross-sectional study of preschool children.
Screening examination for school fitness by physicians of the Public Health Service in Ulm, a city with 100 000 inhabitants in southern Germany.
One thousand two hundred one preschool children.
Infection status was determined by 13C-urea breath test. Information on gastrointestinal symptoms was collected from children's parents by a standardized questionnaire and integrated into a symptom score. Results. Nine hundred forty-five children participated in the study (response rate, 79%). Overall, 127 children (13.4%) were infected. H pylori infection was not positively related to specific gastrointestinal symptomatology. Infected children had even fewer symptoms when compared with uninfected children.
Our results indicate that H pylori infection in children is mostly asymptomatic and not associated with specific gastrointestinal symptoms.
在一个基于健康人群的儿童样本中确定幽门螺杆菌感染与胃肠道症状之间的关系。
对学龄前儿童进行基于人群的横断面研究。
德国南部拥有10万居民的乌尔姆市公共卫生服务部门的医生对儿童进行入学健康筛查。
1201名学龄前儿童。
通过¹³C尿素呼气试验确定感染状况。通过标准化问卷从儿童父母那里收集有关胃肠道症状的信息，并将其纳入症状评分。结果。945名儿童参与了研究（应答率为79%）。总体而言，127名儿童（13.4%）受到感染。幽门螺杆菌感染与特定的胃肠道症状没有正相关关系。与未感染儿童相比，感染儿童的症状甚至更少。
我们的结果表明，儿童幽门螺杆菌感染大多无症状，且与特定的胃肠道症状无关。
