Suppr超能文献

[急性胆源性胰腺炎:微创治疗]

[Acute biliary pancreatitis: mini-invasive treatment].

作者信息

Schietroma M, Lattanzio R, Risetti A, Di Placido R, Carlei F, Cianca G, Cerimele M, Bellucci N, Pistoia M A, Simi M

机构信息

Dipartimento di Discipline Chirurgiche, Università degli Studi di L'Aquila.

出版信息

Chir Ital. 1996;48(4):21-5.

PMID:9522095
Abstract

Acute biliary pancreatitis (ABP) still retains high morbidity (15-50%) and mortality (20-35%). Therefore it appears to be crucial clearly assessing the aetiological factors (50% of idiopathic are in fact biliary pancreatitis) and establishing the severity in order to plan the appropriate treatment. Forty-nine ABP patients were diagnosed by ultrasound (75.5%) or by laboratory findings (22.5%). Following Ranson and APACHE II scoring, 15 cases (30.6%) were classified as severe, 34 (69.3%) as mild. All patients with severe ABP had emergency ERCP + ES (within 24-48 hours) followed by LC (< or = 10 days). Patients with mild ABP had LC within 10 days; in these cases IOC was always done. In severe cases operative endoscopy cured pancreatic inflammation in 11 cases. Subsequent LC never showed serious morbidity, but subcutaneous emphysema in one case. In 4 cases laparotomy was required since pancreatic necrosis was present, with 75% mortality. In patients with mild pancreatitis LC was successfully performed in all cases, with 8.8% morbidity. IOC showed choledochal stones in 32.5% of cases, while in severe cases stones in the biliary tree were showed in 80% of cases. In conclusion ABP treatment is always surgical, and almost always with minimally-invasive procedures in severe cases (ERCP + ES with LC < or = 10 days) if surgery is performed within 24-48 hours as well as in mild cases (LC + IOC) when surgery is done within 10 days.

摘要

急性胆源性胰腺炎(ABP)的发病率(15 - 50%)和死亡率(20 - 35%)仍然居高不下。因此,明确评估病因(50%的特发性胰腺炎实际上是胆源性胰腺炎)并确定严重程度以制定恰当的治疗方案显得至关重要。49例ABP患者通过超声检查确诊(75.5%)或通过实验室检查确诊(22.5%)。根据兰森标准和急性生理与慢性健康状况评分系统II(APACHE II)评分,15例(30.6%)被归类为重症,34例(69.3%)为轻症。所有重症ABP患者均在24 - 48小时内接受急诊内镜逆行胰胆管造影术(ERCP)+内镜括约肌切开术(ES),随后在10天内接受腹腔镜胆囊切除术(LC)。轻症ABP患者在10天内接受LC;在这些病例中均进行了术中胆管造影(IOC)。在重症病例中,手术内镜治疗使11例患者的胰腺炎症得到治愈。随后的LC从未出现严重并发症,但有1例出现皮下气肿。4例因存在胰腺坏死而行剖腹手术,死亡率为75%。在轻症胰腺炎患者中,所有病例的LC均成功实施,并发症发生率为8.8%。IOC显示32.5%的病例存在胆总管结石,而在重症病例中,80%的病例显示胆管树存在结石。总之,ABP的治疗总是需要手术,对于重症病例(如果在24 - 48小时内进行手术,则采用ERCP + ES并在10天内进行LC)以及轻症病例(如果在10天内进行手术,则采用LC + IOC),几乎总是采用微创手术。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验