心脏血液供应的力学原理：右冠状动脉中的波反射效应
Mechanics of blood supply to the heart: wave reflection effects in a right coronary artery.
作者信息
Zamir M
机构信息
Department of Applied Mathematics, University of Western Ontario, London, Canada.
出版信息
Proc Biol Sci. 1998 Mar 7;265(1394):439-44. doi: 10.1098/rspb.1998.0314.
Mechanics of blood flow in the coronary circulation have in the past been based largely on models in which the detailed architecture of the coronary network is not included because of lack of data: properties of individual vessels do not appear individually in the model but are represented collectively by the elements of a single electric circuit. Recent data from the human heart make it possible, for the first time, to examine the dynamics of flow in the coronary network based on detailed, measured vascular architecture. In particular, admittance values along the full course of the right coronary artery are computed based on actual lengths and diameters of the many thousands of branches which make up the distribution system of this vessel. The results indicate that effects of wave reflections on this flow are far more significant than those generally suspected to occur in coronary blood flow and that they are actually the reverse of the well known wave reflection effects in the aorta.
过去，冠状动脉循环中的血流动力学主要基于一些模型，在这些模型中，由于缺乏数据，冠状动脉网络的详细结构未被纳入：单个血管的特性并非单独出现在模型中，而是由单个电路元件共同表示。来自人类心脏的最新数据首次使得基于详细测量的血管结构来研究冠状动脉网络中的血流动力学成为可能。特别是，根据构成该血管分布系统的数千个分支的实际长度和直径，计算出右冠状动脉全程的导纳值。结果表明，波反射对这种血流的影响远比通常认为在冠状动脉血流中发生的影响更为显著，而且实际上与主动脉中众所周知的波反射效应相反。
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