Graham S L, Klistorner A
Save Sight and Eye Health Institute, Department of Ophthamology, Sydney Unversity, New South Wales, Australia.
Aust N Z J Ophthalmol. 1998 Feb;26(1):71-85. doi: 10.1046/j.1440-1606.1998.00082.x.
Because different electrophysiological responses can be isolated to different retinal and cortical cell types and levels, the proportion in which the different signals are reduced can reflect the primary areas of damage. The knowledge of electrophysiology component sources can thus be applied when examining ophthalmic disorders. The present review covers the proposed origins and the usefulness of the conventional electrophysiological responses. Their application to glaucoma is discussed, with particular reference to the pattern electroretinogram. In the second part of the current review, we present some recent developments that relate to the use of multifocal pseudorandomly stimulated recording. This technique enables a new approach to the electrical assessment of visual responses. Analysis for temporal non-linearities and spatial distribution of the response throughout the visual field can be implemented. This type of recording has the potential to provide a method of objective visual field assessment in glaucoma and other disorders of the visual system.
由于不同的电生理反应可归因于不同的视网膜和皮质细胞类型及水平，不同信号减少的比例能够反映损伤的主要区域。因此，在检查眼科疾病时，可应用电生理学成分来源的相关知识。本综述涵盖了传统电生理反应的推测起源及用途。讨论了它们在青光眼方面的应用，尤其提及图形视网膜电图。在本综述的第二部分，我们介绍了一些与使用多焦点伪随机刺激记录相关的最新进展。这项技术为视觉反应的电评估提供了一种新方法。可以对整个视野中反应的时间非线性和空间分布进行分析。这种记录方式有可能为青光眼及其他视觉系统疾病提供一种客观视野评估方法。
