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J Antimicrob Chemother. 1996 Aug;38(2):271-81. doi: 10.1093/jac/38.2.271.
2
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Eur J Clin Microbiol Infect Dis. 1993 Aug;12(8):640-2. doi: 10.1007/BF01973648.
3
Susceptibilities of 428 gram-positive and -negative anaerobic bacteria to Bay y3118 compared with their susceptibilities to ciprofloxacin, clindamycin, metronidazole, piperacillin, piperacillin-tazobactam, and cefoxitin.428株革兰氏阳性和阴性厌氧菌对Bay y3118的敏感性及其对环丙沙星、克林霉素、甲硝唑、哌拉西林、哌拉西林-他唑巴坦和头孢西丁的敏感性比较。
Antimicrob Agents Chemother. 1993 Aug;37(8):1649-54. doi: 10.1128/AAC.37.8.1649.
4
Comparative activities of eight quinolones against members of the Bacteroides fragilis group.八种喹诺酮类药物对脆弱拟杆菌群成员的比较活性
Antimicrob Agents Chemother. 1994 Jun;38(6):1442-5. doi: 10.1128/AAC.38.6.1442.
5
In-vitro activity of clinafloxacin (CI-960) and PD 131628-2 against anaerobic bacteria.克林沙星（CI-960）和PD 131628-2对厌氧菌的体外活性
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6
In vitro activity of DU-6859a against anaerobic bacteria.DU-6859a对厌氧菌的体外活性。
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The laboratory identification of gram-positive anaerobic cocci.革兰氏阳性厌氧球菌的实验室鉴定
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Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria.环丙沙星、氧氟沙星、司帕沙星、替马沙星、CI-960、CI-990和WIN 57273对厌氧菌的比较活性。
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A simple and sensitive technique for determining and fermentation reactions of non-sporing anaerobes.一种用于测定非芽孢厌氧菌发酵反应的简单且灵敏的技术。
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新型7-取代氟喹诺酮类药物Y-688对厌氧菌的体外活性

In vitro activities of Y-688, a new 7-substituted fluoroquinolone, against anaerobic bacteria.

作者信息

MacGowan A P, Bowker K E, Wootton M, Holt H A, Reeves D S

机构信息

Bristol Centre for Antimicrobial Research and Evaluation, University of Bristol, Department of Medical Microbiology, Southmead Hospital, Westbury-on-Trym, United Kingdom.

出版信息

Antimicrob Agents Chemother. 1998 Feb;42(2):419-24. doi: 10.1128/AAC.42.2.419.

DOI:10.1128/AAC.42.2.419
PMID:9527797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC105425/
Abstract

The in vitro activities of Y-688, a new 7-substituted fluoroquinolone derivative, against 317 nonduplicate anaerobic isolates were determined. Eighty-five percent of the Bacteroides fragilis group (n = 89) were inhibited by < or = 2 mg of Y-688 per liter, while 78, 100, 89, and 98% of gram-negative bacilli (n = 135), gram-positive cocci (n = 59), and non-spore-forming (n = 58) and spore-forming (n = 51) gram-positive bacilli, respectively, were inhibited by < or = 1 mg of Y-688 per liter.

摘要

测定了新型7-取代氟喹诺酮衍生物Y-688对317株非重复厌氧分离株的体外活性。每升含≤2毫克Y-688时，85%的脆弱拟杆菌群（n = 89）受到抑制，而每升含≤1毫克Y-688时，分别有78%的革兰氏阴性杆菌（n = 135）、100%的革兰氏阳性球菌（n = 59）、89%的无芽孢革兰氏阳性杆菌（n = 58）和98%的芽孢革兰氏阳性杆菌（n = 51）受到抑制。