• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

蜱免疫豚鼠中的粒细胞埃立克体病

Granulocytic ehrlichiosis in tick-immune guinea pigs.

作者信息

Das S, Deponte K, Marcantonio N L, Ijdo J W, Hodzic E, Katavolos P, Barthold S W, Telford S R, Kantor F S, Fikrig E

机构信息

Department of Internal Medicine, Yale University, New Haven, Connecticut 06520-8031, USA.

出版信息

Infect Immun. 1998 Apr;66(4):1803-5. doi: 10.1128/IAI.66.4.1803-1805.1998.

DOI:10.1128/IAI.66.4.1803-1805.1998
PMID:9529119
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC108126/
Abstract

We investigated whether Ixodes scapularis-mediated host immunity interrupts transmission of the agent of human granulocytic ehrlichiosis (aoHGE) to guinea pigs. Ticks infected with aoHGE readily transmitted aoHGE to tick-immune guinea pigs, despite incomplete tick engorgement and host attachment. Although tick immunity can prevent Lyme borreliosis, protection is not afforded against granulocytic ehrlichiosis.

摘要

我们研究了肩突硬蜱介导的宿主免疫是否会中断人粒细胞埃立克体病病原体(aoHGE)向豚鼠的传播。尽管蜱虫未完全饱血且未牢固附着在宿主体上,但感染了aoHGE的蜱虫仍能轻易地将aoHGE传播给对蜱虫免疫的豚鼠。虽然蜱虫免疫可以预防莱姆病,但对粒细胞埃立克体病却没有防护作用。

相似文献

1
Granulocytic ehrlichiosis in tick-immune guinea pigs.蜱免疫豚鼠中的粒细胞埃立克体病
Infect Immun. 1998 Apr;66(4):1803-5. doi: 10.1128/IAI.66.4.1803-1805.1998.
2
Immunization against the agent of human granulocytic ehrlichiosis in a murine model.在小鼠模型中针对人粒细胞埃立克体病病原体的免疫接种
J Clin Invest. 1997 Dec 15;100(12):3014-8. doi: 10.1172/JCI119855.
3
Acquisition dynamics of Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis at the host-vector interface.伯氏疏螺旋体及人粒细胞埃立克体病病原体在宿主-媒介界面的获取动态。
Vector Borne Zoonotic Dis. 2001 Summer;1(2):149-58. doi: 10.1089/153036601316977750.
4
Acquisition and transmission of the agent of human granulocytic ehrlichiosis by Ixodes scapularis ticks.肩突硬蜱传播人粒细胞无形体病病原体及该病原体的获得
J Clin Microbiol. 1998 Dec;36(12):3574-8. doi: 10.1128/JCM.36.12.3574-3578.1998.
5
Coinfection with Borrelia burgdorferi and the agent of human granulocytic ehrlichiosis suppresses IL-2 and IFN gamma production and promotes an IL-4 response in C3H/HeJ mice.伯氏疏螺旋体与人类粒细胞埃立克体病病原体的共同感染会抑制C3H/HeJ小鼠中白细胞介素-2和γ干扰素的产生,并促进白细胞介素-4反应。
Parasite Immunol. 2000 Nov;22(11):581-8. doi: 10.1046/j.1365-3024.2000.00339.x.
6
Transmission of the agent of human granulocytic ehrlichiosis by Ixodes spinipalpis ticks: evidence of an enzootic cycle of dual infection with Borrelia burgdorferi in Northern Colorado.斯氏硬蜱传播人粒细胞埃立克体病病原体:科罗拉多州北部存在伯氏疏螺旋体双重感染自然疫源地循环的证据
J Infect Dis. 2000 Aug;182(2):616-9. doi: 10.1086/315715. Epub 2000 Jul 28.
7
Use of a sentinel host system to study the questing behavior of Ixodes spinipalpis and its role in the transmission of Borrelia bissettii, human granulocytic ehrlichiosis, and Babesia microti.使用哨兵宿主系统研究棘背硬蜱的 questing 行为及其在伯氏疏螺旋体、人粒细胞埃立克体病和微小巴贝斯虫传播中的作用。 (注:questing 这个词可能在医学昆虫学领域有特定含义,可能是指蜱类等待宿主的某种行为状态,这里直接保留英文以便准确传达原文信息)
Am J Trop Med Hyg. 2001 Oct;65(4):293-9. doi: 10.4269/ajtmh.2001.65.293.
8
Pathogen transmission in relation to duration of attachment by Ixodes scapularis ticks.硬蜱附着时间与病原体传播的关系。
Ticks Tick Borne Dis. 2018 Mar;9(3):535-542. doi: 10.1016/j.ttbdis.2018.01.002. Epub 2018 Jan 31.
9
Transmission of Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in horses using experimentally infected ticks (Ixodes scapularis).利用实验感染蜱(肩突硬蜱)在马体内传播嗜吞噬细胞无形体(人类粒细胞埃立克体病原体)
J Vet Med B Infect Dis Vet Public Health. 2002 Dec;49(10):484-8. doi: 10.1046/j.1439-0450.2002.00598.x.
10
Effect of tick removal on transmission of Borrelia burgdorferi and Ehrlichia phagocytophila by Ixodes scapularis nymphs.去除蜱虫对肩突硬蜱若虫传播伯氏疏螺旋体和嗜吞噬细胞无形体的影响。
J Infect Dis. 2001 Mar 1;183(5):773-8. doi: 10.1086/318818. Epub 2001 Feb 1.

引用本文的文献

1
Laboratory Management of Mammalian Hosts for -Host-Pathogen Interaction Studies.用于 -宿主-病原体相互作用研究的哺乳动物宿主的实验室管理。
Comp Med. 2024 Aug 1;74(4):235-245. doi: 10.30802/AALAS-CM-24-036.
2
Specific expression of Anaplasma marginale major surface protein 2 salivary gland variants occurs in the midgut and is an early event during tick transmission.边缘无形体主要表面蛋白2唾液腺变体的特异性表达发生在中肠,是蜱传播过程中的早期事件。
Infect Immun. 2002 Jan;70(1):114-20. doi: 10.1128/IAI.70.1.114-120.2002.
3
Immunity reduces reservoir host competence of Peromyscus leucopus for Ehrlichia phagocytophila.免疫力降低了白足鼠作为嗜吞噬细胞无形体储存宿主的能力。
Infect Immun. 2000 Mar;68(3):1514-8. doi: 10.1128/IAI.68.3.1514-1518.2000.
4
Effect of prior exposure to noninfected ticks on susceptibility of mice to Lyme disease spirochetes.先前暴露于未感染蜱虫对小鼠感染莱姆病螺旋体易感性的影响。
Appl Environ Microbiol. 1998 Nov;64(11):4596-9. doi: 10.1128/AEM.64.11.4596-4599.1998.

本文引用的文献

1
Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity.通过蜱免疫预防豚鼠感染伯氏疏螺旋体。
Am J Trop Med Hyg. 1998 Jun;58(6):780-5. doi: 10.4269/ajtmh.1998.58.780.
2
Granulocytic ehrlichiosis in the laboratory mouse.
J Infect Dis. 1998 Mar;177(3):737-45. doi: 10.1086/514236.
3
The early humoral response in human granulocytic ehrlichiosis.人粒细胞埃立克体病的早期体液免疫反应。
J Infect Dis. 1997 Sep;176(3):687-92. doi: 10.1086/514091.
4
Prevalence of the rickettsial agent of human granulocytic ehrlichiosis in ticks from a hyperendemic focus of Lyme disease.莱姆病高度流行区蜱中人类粒细胞埃立克体病立克次氏体病原体的流行情况
N Engl J Med. 1997 Jul 3;337(1):49-50. doi: 10.1056/NEJM199707033370111.
5
Infestation with pathogen-free nymphs of the tick Ixodes scapularis induces host resistance to transmission of Borrelia burgdorferi by ticks.用无病原体的肩突硬蜱若虫侵染可诱导宿主对蜱传播伯氏疏螺旋体产生抗性。
Infect Immun. 1997 Jan;65(1):335-8. doi: 10.1128/iai.65.1.335-338.1997.
6
Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle.人粒细胞埃立克体病病原体在鹿蜱-啮齿动物循环中的持续存在。
Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):6209-14. doi: 10.1073/pnas.93.12.6209.
7
Human granulocytic ehrlichiosis in Wisconsin and Minnesota: a frequent infection with the potential for persistence.威斯康星州和明尼苏达州的人类粒细胞埃立克体病:一种常见且可能持续存在的感染。
J Infect Dis. 1996 Apr;173(4):1027-30. doi: 10.1093/infdis/173.4.1027.
8
Coexistence of antibodies to tick-borne pathogens of babesiosis, ehrlichiosis, and Lyme borreliosis in human sera.人体血清中存在针对巴贝斯虫病、埃立克体病和莱姆病的蜱传病原体的抗体。
J Clin Microbiol. 1995 Nov;33(11):3054-7. doi: 10.1128/jcm.33.11.3054-3057.1995.
9
Acquired resistance in dogs to repeated infestation with Ixodes scapularis (Acari: Ixodidae) reduces tick viability and reproductive success.犬对肩突硬蜱(蜱螨亚纲:硬蜱科)反复侵染产生的获得性抗性会降低蜱的活力和繁殖成功率。
Exp Appl Acarol. 1995 Oct;19(10):593-605. doi: 10.1007/BF00048814.
10
Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine.伯氏疏螺旋体OspA是一种针对节肢动物的、可阻断传播的莱姆病疫苗。
J Exp Med. 1996 Jan 1;183(1):271-5. doi: 10.1084/jem.183.1.271.