青光眼性视神经乳头地形图测量的可重复性。
Reproducibility of topographic measures of the glaucomatous optic nerve head.
作者信息
Geyer O, Michaeli-Cohen A, Silver D M, Versano D, Neudorfer M, Dzhanov R, Lazar M
机构信息
Department of Ophthalmology, Sourasky Medical Center, Tel-Aviv University, Israel.
出版信息
Br J Ophthalmol. 1998 Jan;82(1):14-7. doi: 10.1136/bjo.82.1.14.
AIMS/BACKGROUND: Laser scanning tomography provides an assessment of three dimensional optic disc topography. For the clinical purpose of follow up of glaucoma patients, the repeatability of the various measured variables is essential. In the present study, the reproducibility of morphometric variables calculated by the topographic scanning system, TopSS (Laser Diagnostic Technology, San Diego, CA) was investigated.
METHODS
Two independent measurements (30 minutes apart) each consisting of three complete images of the optic disc were performed on 16 eyes of 16 glaucoma patients using a TopSS. The instrument calculates 14 morphometric variables for the characterisation of the optic disc.
RESULTS
From the two tailed paired tests, all variables were seen to have good reproducibility. However, correlation and regression analyses showed that only the three variables, volume below, half depth area, and average cup depth, are acceptably reproducible.
CONCLUSION
The TopSS provides three variables which describe the physiological shape of the optic disc that have high reproducibility. These three variables might be useful for following the progression of optic disc changes in glaucoma patients.
目的/背景：激光扫描断层扫描可对三维视盘地形图进行评估。对于青光眼患者随访的临床目的而言，各种测量变量的可重复性至关重要。在本研究中，对由地形扫描系统TopSS（激光诊断技术公司，加利福尼亚州圣地亚哥）计算得出的形态计量学变量的可重复性进行了研究。
方法
使用TopSS对16例青光眼患者的16只眼睛进行了两次独立测量（间隔30分钟），每次测量包括视盘的三张完整图像。该仪器计算14个形态计量学变量以表征视盘。
结果
从双尾配对检验来看，所有变量均具有良好的可重复性。然而，相关性和回归分析表明，只有以下三个变量，即下方体积、半深度面积和平均杯深，具有可接受的可重复性。
结论
TopSS提供了三个描述视盘生理形状且具有高可重复性的变量。这三个变量可能有助于追踪青光眼患者视盘变化的进展情况。
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