• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基底神经节的神经元回路与突触连接

Neuronal circuitry and synaptic connectivity of the basal ganglia.

作者信息

Smith Y, Shink E, Sidibé M

机构信息

Yerkes Regional Primate Center, Emory University School of Medicine, Atlanta, Georgia 30329, USA.

出版信息

Neurosurg Clin N Am. 1998 Apr;9(2):203-22.

PMID:9556359
Abstract

The concept of organization of the basal ganglia has changed markedly over the last 10 years. These developments have led to the introduction of a schematic model of the functional circuitry of the basal ganglia that accounts for normal and abnormal basal ganglia functions. The recent introduction of powerful techniques for the analysis of neuronal networks has led to many new developments in our understanding of the anatomic and synaptic organization of the basal ganglia. The objective of this article is to go from the established model of the basal ganglia connectivity to new anatomic findings that lead to reconsideration and refinement of some aspects of the models.

摘要

在过去十年中,基底神经节的组织概念发生了显著变化。这些进展促使引入了一种基底神经节功能回路的示意图模型,该模型解释了基底神经节的正常和异常功能。最近用于分析神经元网络的强大技术的引入,在我们对基底神经节的解剖和突触组织的理解方面带来了许多新进展。本文的目的是从已建立的基底神经节连接模型转向新的解剖学发现,这些发现促使对模型的某些方面进行重新思考和完善。

相似文献

1
Neuronal circuitry and synaptic connectivity of the basal ganglia.基底神经节的神经元回路与突触连接
Neurosurg Clin N Am. 1998 Apr;9(2):203-22.
2
Microcircuitry of the direct and indirect pathways of the basal ganglia.基底神经节直接和间接通路的微回路。
Neuroscience. 1998 Sep;86(2):353-87. doi: 10.1016/s0306-4522(98)00004-9.
3
Anatomical funneling, sparse connectivity and redundancy reduction in the neural networks of the basal ganglia.基底神经节神经网络中的解剖学漏斗效应、稀疏连接性和冗余减少
J Physiol Paris. 2003 Jul-Nov;97(4-6):581-9. doi: 10.1016/j.jphysparis.2004.01.015.
4
Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia function.基底神经节中GABA功能的模拟:基底神经节功能中GABA能机制的计算模型。
Prog Brain Res. 2007;160:313-29. doi: 10.1016/S0079-6123(06)60018-6.
5
Self-organization in the basal ganglia with modulation of reinforcement signals.基底神经节中的自组织与强化信号的调制
Neural Comput. 2002 Apr;14(4):819-44. doi: 10.1162/089976602317318974.
6
Synaptic plasticity in the basal ganglia.基底神经节中的突触可塑性。
Behav Brain Res. 2009 Apr 12;199(1):119-28. doi: 10.1016/j.bbr.2008.10.030. Epub 2008 Nov 6.
7
Modeling the organization of the basal ganglia.模拟基底神经节的组织结构。
Rev Neurol (Paris). 2008 Dec;164(12):969-76. doi: 10.1016/j.neurol.2008.04.019. Epub 2008 Jul 9.
8
Autonomous pacemakers in the basal ganglia: who needs excitatory synapses anyway?基底神经节中的自主起搏器:到底谁需要兴奋性突触呢?
Curr Opin Neurobiol. 2005 Jun;15(3):312-8. doi: 10.1016/j.conb.2005.05.007.
9
Seven problems on the basal ganglia.基底神经节的七个问题。
Curr Opin Neurobiol. 2008 Dec;18(6):595-604. doi: 10.1016/j.conb.2008.11.001. Epub 2008 Dec 8.
10
Real-time simulation of a spiking neural network model of the basal ganglia circuitry using general purpose computing on graphics processing units.使用通用图形处理单元进行基于尖峰神经网络模型的基底神经节电路的实时仿真。
Neural Netw. 2011 Nov;24(9):950-60. doi: 10.1016/j.neunet.2011.06.008. Epub 2011 Jun 30.

引用本文的文献

1
Dopaminergic Nigrostriatal Connectivity in Early Parkinson Disease: In Vivo Neuroimaging Study of C-DTBZ PET Combined with Correlational Tractography.早期帕金森病的多巴胺能黑质纹状体连接:C-DTBZ PET 与相关纤维束成像的体内神经影像学研究。
J Nucl Med. 2021 Apr;62(4):545-552. doi: 10.2967/jnumed.120.248500. Epub 2020 Aug 28.
2
Loss and remodeling of striatal dendritic spines in Parkinson's disease: from homeostasis to maladaptive plasticity?帕金森病纹状体树突棘的丢失和重塑:从内稳态到适应不良的可塑性?
J Neural Transm (Vienna). 2018 Mar;125(3):431-447. doi: 10.1007/s00702-017-1735-6. Epub 2017 May 24.
3
The role of the human globus pallidus in Huntington's disease.
人类苍白球在亨廷顿舞蹈病中的作用。
Brain Pathol. 2016 Nov;26(6):741-751. doi: 10.1111/bpa.12429.
4
Corticostriatal circuitry.皮质纹状体回路
Dialogues Clin Neurosci. 2016 Mar;18(1):7-21. doi: 10.31887/DCNS.2016.18.1/shaber.
5
The external globus pallidus: progress and perspectives.外侧苍白球:进展与展望
Eur J Neurosci. 2016 May;43(10):1239-65. doi: 10.1111/ejn.13196. Epub 2016 Mar 28.
6
Morphological changes of glutamatergic synapses in animal models of Parkinson's disease.帕金森病动物模型中谷氨酸能突触的形态学变化。
Front Neuroanat. 2015 Sep 25;9:117. doi: 10.3389/fnana.2015.00117. eCollection 2015.
7
Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.小白蛋白阳性神经元和Npas1阳性神经元是小鼠外侧苍白球中不同的神经元类别。
J Neurosci. 2015 Aug 26;35(34):11830-47. doi: 10.1523/JNEUROSCI.4672-14.2015.
8
Common therapeutic mechanisms of pallidal deep brain stimulation for hypo- and hyperkinetic movement disorders.苍白球深部脑刺激治疗运动减少型和运动增多型运动障碍的常见治疗机制。
J Neurophysiol. 2015 Oct;114(4):2090-104. doi: 10.1152/jn.00223.2015. Epub 2015 Jul 15.
9
Diffusion tensor imaging of the nigrostriatal fibers in Parkinson's disease.帕金森病中黑质纹状体纤维的扩散张量成像
Mov Disord. 2015 Aug;30(9):1229-36. doi: 10.1002/mds.26251. Epub 2015 Apr 29.
10
Transgenic mouse lines subdivide external segment of the globus pallidus (GPe) neurons and reveal distinct GPe output pathways.转基因鼠系可细分苍白球外节(GPe)神经元,并揭示出不同的 GPe 输出通路。
J Neurosci. 2014 Feb 5;34(6):2087-99. doi: 10.1523/JNEUROSCI.4646-13.2014.