Anttila S S, Knuuttila M L, Sakki T K
Department of Periodontology and Geriatric Dentistry, Institute of Dentistry, University of Oulu, Finland.
Psychosom Med. 1998 Mar-Apr;60(2):215-8. doi: 10.1097/00006842-199803000-00018.
The purpose of this survey was to study the sensation of oral dryness and its underlying factors in the 55-year-old population of Oulu (a medium-sized Finnish town), 780 of whom (77%) participated.
In addition to the examination of oral health status and salivary flow rate measurements, depressive symptoms were determined on the basis of the Zung Self-Rating Depression Scale (ZSDS). The participants were also interviewed about their health, medication, physical health, physical activity, smoking habits, alcohol consumption, and factors related to their work.
The prevalence of subjective sensations of dry mouth was 25.8% among men and 33.3% among women (p = 0.025). A statistically significant association was found between a subjective sensation of dry mouth and a low unstimulated flow rate, regular smoking, xerogenic medication, and the presence of at least one illness connected with dry mouth. Those who had a sensation of dry mouth also thought their physical condition and their health to be poorer and more often had a high rate of depressive symptoms. After the confounding factors had been added stepwise into the logistic regression model, depressive symptoms were still significantly associated with the sensation of oral dryness.
When evaluating the causes of the sensation of dry mouth, the possibility of depression as an underlying factor should be considered.
本次调查旨在研究芬兰中等规模城镇奥卢55岁人群的口腔干燥感及其潜在因素，其中780人（77%）参与了调查。
除了检查口腔健康状况和测量唾液流速外，还根据zung自评抑郁量表（ZSDS）确定抑郁症状。参与者还接受了关于他们的健康、用药、身体健康、体育活动、吸烟习惯、饮酒情况以及与工作相关因素的访谈。
男性主观口干感的患病率为25.8%，女性为33.3%（p = 0.025）。在主观口干感与低静息流速、经常吸烟、致口干药物以及至少一种与口干相关疾病的存在之间发现了统计学上的显著关联。有口干感的人也认为他们的身体状况和健康较差，并且更经常有较高的抑郁症状发生率。在逐步将混杂因素纳入逻辑回归模型后，抑郁症状仍与口腔干燥感显著相关。
在评估口干感的原因时，应考虑抑郁作为潜在因素的可能性。
