Goldstein L B
Department of Medicine (Neurology) Veterans Affairs Medical Center and Center for Clinical Health Policy Research, Duke University, Durham, NC 27710, USA.
Arch Neurol. 1998 Apr;55(4):454-6. doi: 10.1001/archneur.55.4.454.
Studies in laboratory animals clearly show that the rate and extent of functional recovery after focal brain injury can be modulated by drugs affecting certain neurotransmitters in the central nervous system. Preliminary clinical studies suggest that similar drug effects occur in humans recovering from stroke. Understanding these pharmacological effects is important because several of the classes of drugs that impair recovery in laboratory experiments are used to treat coincident medical problems in patients who have had a stroke.
对实验动物的研究清楚地表明,局灶性脑损伤后功能恢复的速度和程度可通过影响中枢神经系统某些神经递质的药物来调节。初步临床研究表明,中风康复患者身上也会出现类似的药物作用。了解这些药理作用很重要,因为在实验室实验中阻碍恢复的几类药物被用于治疗中风患者同时出现的医疗问题。