Mougios V, Kouidi E, Kyparos A, Deligiannis A
Department of Physical Education and Sports Science, University of Thessaloniki, Greece.
Br J Sports Med. 1998 Mar;32(1):58-62. doi: 10.1136/bjsm.32.1.58.
To examine whether prolonged moderate exercising by untrained middle aged individuals of both sexes affects the plasma ratio of unsaturated to saturated (U/S) fatty acids in the non-esterified fatty acid (NEFA) and triacylglycerol (TG) fractions.
Twenty two healthy untrained volunteers (eleven men and eleven pre-menopausal women), aged 35-55, exercised on bicycles at 50-55% maximal heart rate reserve (estimated 61% maximal oxygen uptake) for one hour. Pre- and post-exercise blood samples were analysed for lactate, glucose, glycerol, individual NEFAs and TG acyl groups, cholesterol, high density lipoprotein cholesterol, urea, cortisol, and testosterone. Biopsy specimens of adipose tissue were analysed for TG acyl group composition.
Serum total NEFAs increased significantly whereas total TG decreased significantly in both sexes. Changes in individual fatty acids, in both the NEFA and TG fractions, generally paralleled changes in the total pool but were not proportionate. As a result, U/S NEFAs increased in both sexes, although significantly only in women. The shift was in the direction of the composition of the major source of blood NEFAs--that is, adipose tissue TG. U/S acyl groups of TG also increased in both sexes, although significantly only in men.
Prolonged moderate exercise increases the U/S ratio of serum NEFAs and TG. This may add to the beneficial effects of exercise given the protective role of unsaturated fatty acids against coronary heart disease.
研究未经训练的中年男女进行长时间适度运动是否会影响非酯化脂肪酸（NEFA）和三酰甘油（TG）组分中不饱和脂肪酸与饱和脂肪酸（U/S）的血浆比例。
22名年龄在35 - 55岁之间、未经训练的健康志愿者（11名男性和11名绝经前女性）以最大心率储备的50 - 55%（估计最大摄氧量的61%）在自行车上运动1小时。运动前后的血样分析了乳酸、葡萄糖、甘油、个体NEFAs和TG酰基、胆固醇、高密度脂蛋白胆固醇、尿素、皮质醇和睾酮。对脂肪组织活检标本进行TG酰基组成分析。
男女两性血清总NEFAs显著增加而总TG显著降低。NEFA和TG组分中单个脂肪酸的变化一般与总库的变化平行，但不成比例。结果，男女两性U/S NEFAs均增加，不过仅女性增加显著。这种变化方向与血液NEFAs的主要来源即脂肪组织TG的组成一致。TG的U/S酰基在男女两性中也增加，不过仅男性增加显著。
长时间适度运动可提高血清NEFAs和TG的U/S比例。鉴于不饱和脂肪酸对冠心病的保护作用，这可能会增加运动的有益效果。
