Suppr超能文献

乳糜泻患者的燕麦和大麦毒性

Oats and barley toxicity in coeliac patients.

作者信息

Baker P G, Read A E

出版信息

Postgrad Med J. 1976 May;52(607):264-8. doi: 10.1136/pgmj.52.607.264.

Abstract

The effect of addition of oats and barley to the glutenfree diets of a group of patients with coeliac disease has been studied using the oral 5 g xylose excretion test to assess small bowel function before and after these supplementations. Both oats and barley were found to be potentially harmful to coeliac patients although the toxic effect of barley was more readily produced than that of oats. On the basis of their results, the authors recommend the exclusion of both barley and oats, in addition to wheat and rye, from the coeliac diet. In view of the well recognized risk of the development of malignancy, such a diet should be followed particularly rigorously in those patients with a persistence of symptoms and of marked villous atrophy.

摘要

通过口服5克木糖排泄试验评估一组乳糜泻患者在无麸质饮食中添加燕麦和大麦前后的小肠功能,研究了添加燕麦和大麦的效果。结果发现,燕麦和大麦对乳糜泻患者均有潜在危害,尽管大麦的毒性作用比燕麦更容易产生。基于研究结果,作者建议除了小麦和黑麦之外,乳糜泻患者的饮食中也应排除大麦和燕麦。鉴于已充分认识到发生恶性肿瘤的风险,对于那些症状持续且存在明显绒毛萎缩的患者,应特别严格地遵循这种饮食。

相似文献

1
Oats and barley toxicity in coeliac patients.
Postgrad Med J. 1976 May;52(607):264-8. doi: 10.1136/pgmj.52.607.264.
3
Contact dermatitis from barley dust.
Contact Dermatitis. 1979 May;5(3):196. doi: 10.1111/j.1600-0536.1979.tb04848.x.
4
Demonstration of the presence of coeliac-activating gliadin-like epitopes in malted barley.
Int Arch Allergy Immunol. 1994 Jul;104(3):308-10. doi: 10.1159/000236683.
5
Letter: Oats and coeliac disease.
Br Med J. 1975 Jan 18;1(5950):152. doi: 10.1136/bmj.1.5950.152-a.
7
Considering wheat, rye, and barley proteins as aids to carcinogens.
Med Hypotheses. 1997 Sep;49(3):285-8. doi: 10.1016/s0306-9877(97)90215-2.
8
Lack of harmful effect of oats on small-intestinal mucosa in coeliac disease.
Br Med J. 1974 Oct 26;4(5938):189-91. doi: 10.1136/bmj.4.5938.189.
10
Role of oats in celiac disease.
World J Gastroenterol. 2015 Nov 7;21(41):11825-31. doi: 10.3748/wjg.v21.i41.11825.

引用本文的文献

1
To Be Oats or Not to Be? An Update on the Ongoing Debate on Oats for Patients With Celiac Disease.
Front Pediatr. 2019 Sep 26;7:384. doi: 10.3389/fped.2019.00384. eCollection 2019.
2
The gluten-free diet and its current application in coeliac disease and dermatitis herpetiformis.
United European Gastroenterol J. 2015 Apr;3(2):121-35. doi: 10.1177/2050640614559263.
3
Nutritional advantages of oats and opportunities for its processing as value added foods - a review.
J Food Sci Technol. 2015 Feb;52(2):662-75. doi: 10.1007/s13197-013-1072-1. Epub 2013 Jun 25.
4
The clinical response to gluten challenge: a review of the literature.
Nutrients. 2013 Nov 19;5(11):4614-41. doi: 10.3390/nu5114614.
5
Degradation of coeliac disease-inducing rye secalin by germinating cereal enzymes: diminishing toxic effects in intestinal epithelial cells.
Clin Exp Immunol. 2010 Aug;161(2):242-9. doi: 10.1111/j.1365-2249.2010.04119.x. Epub 2010 Jun 15.
6
8
Pathogenesis of coeliac disease: implications for treatment.
World J Gastroenterol. 2001 Dec;7(6):772-6. doi: 10.3748/wjg.v7.i6.772.
9
Celiac Disease.
Curr Treat Options Gastroenterol. 2002 Feb;5(1):27-38. doi: 10.1007/s11938-002-0004-3.

本文引用的文献

1
The place of oats in the coeliac diet.
Arch Dis Child. 1959 Feb;34(173):51-5. doi: 10.1136/adc.34.173.51.
2
Coeliac disease. V. Some experiments on the cause of the harmful effect of wheat gliadin.
Acta Paediatr (Stockh). 1955 Sep;44(5):465-9. doi: 10.1111/j.1651-2227.1955.tb04269.x.
3
Coeliac disease.
Lancet. 1955 Nov 26;269(6900):1097-103. doi: 10.1016/s0140-6736(55)92946-9.
5
Childhood celiac disease: response of treated patients to a small uniform daily dose of wheat gluten.
J Pediatr. 1972 Nov;81(5):885-93. doi: 10.1016/s0022-3476(72)80538-9.
6
Coeliac disease. The small intestine at autopsy.
Clin Gastroenterol. 1974 Jan;3(1):171-81.
7
Lack of harmful effect of oats on small-intestinal mucosa in coeliac disease.
Br Med J. 1974 Oct 26;4(5938):189-91. doi: 10.1136/bmj.4.5938.189.
8
Testing gluten sensitivity by the xylose test.
Lancet. 1972 Mar 25;1(7752):667-8. doi: 10.1016/s0140-6736(72)90466-7.
9
Detection of continuing gluten ingestion in treated coeliac patients.
Br Med J. 1975 Mar 1;1(5956):486-8. doi: 10.1136/bmj.1.5956.486.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验